Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.58 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9420493 | 1.00 | ADRB2 (0.58) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL11615833 | 0.95 | ADRB2 (0.64) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL3185659 | 0.90 | ADRB2 (0.49) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL10439554 | 0.84 | ADRB2 (0.68) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL7023482 | 0.82 | ADRB2 (0.68) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL11863154 | 0.81 | L3MBTL1 (0.56) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL5015380 | 0.81 | ADRB2 (0.55) | ADRB2ADRB1ADRB3ALDH1A1MAPT | |
| SCHEMBL15512326 | 0.80 | ALDH1A1 (0.56) | ADRB2ADRB1ADRB3KMT2AALDH1A1 | |
| SCHEMBL6062795 | 0.80 | ALDH1A1 (0.56) | ADRB2ADRB1ADRB3KMT2AALDH1A1 | |
| SCHEMBL15512256 | 0.80 | ALDH1A1 (0.56) | ADRB2ADRB1ADRB3KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328585-B1 | METABOLICALLY ACCEPTABLE POLYISOCYANATE ADHESIVES | BIORESEARCH INC (US) | 1994-09-07 | — | — | EP | disclosed |
| EP-0328585-A4 | METABOLICALLY ACCEPTABLE POLYISOCYANATE ADHESIVES | — | 1991-06-05 | — | — | EP | disclosed |
| EP-0328585-A1 | METABOLICALLY ACCEPTABLE POLYISOCYANATE ADHESIVES | BIORESEARCH INC. (US) | 1989-08-23 | — | — | EP | disclosed |
| US-4829099-A | SURGERY, POLYISOCYANATES, POLYISOTHIOCYANATES | BIORESEARCH, INC. (US) | 1989-05-09 | — | — | US | disclosed |
| WO-1989000589-A1 | METABOLICALLY ACCEPTABLE POLYISOCYANATE ADHESIVES | BIORESEARCH, INC. (US) | 1989-01-26 | — | — | WO | disclosed |