SCHEMBL5015380

SCHEMBL5015380

CC(COC(=O)c1ccc(N)cc1)OCC(C)OC(=O)c1ccc(N)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 5/20 0.55
ADRB1 P08588 5/20 0.55
ADRB3 P13945 5/20 0.55
LMNA P02545 3/20 0.53
CYP1A2 P05177 3/20 0.53
CYP3A4 P08684 3/20 0.53
MAOA P21397 2/20 0.53
SCN1A P35498 2/20 0.49
SCN2A Q99250 2/20 0.49
SCN3A Q9NY46 2/20 0.49
TSHR P16473 2/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
PDE4D Q08499 1/20 0.48
PHLPP2 Q6ZVD8 1/20 0.47
MAPT P10636 2/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
ALDH1A1 P00352 2/20 0.46
CYP2D6 P10635 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9420534 0.99 ADRB2 (0.53) ADRB2ADRB1ADRB3LMNACYP1A2
SCHEMBL369461 0.94 ADRB2 (0.60) ADRB2ADRB1ADRB3LMNACYP1A2
Ethylene Glycol SCHEMBL1049002 0.90 ADRB2 (0.56) ADRB2ADRB1ADRB3LMNACYP1A2
SCHEMBL3180950 0.88 SCN1A (0.46) ADRB2ADRB1ADRB3LMNACYP1A2
SCHEMBL15512148 0.85 ALDH1A1 (0.56) ADRB2ADRB1ADRB3LMNACYP1A2
SCHEMBL6062795 0.85 ALDH1A1 (0.56) ADRB2ADRB1ADRB3LMNACYP1A2
SCHEMBL15512326 0.85 ALDH1A1 (0.56) ADRB2ADRB1ADRB3LMNACYP1A2
SCHEMBL15512256 0.85 ALDH1A1 (0.56) ADRB2ADRB1ADRB3LMNACYP1A2
SCHEMBL115001 0.85 ALDH1A1 (0.56) ADRB2ADRB1ADRB3LMNACYP1A2
SCHEMBL30789021 0.85 ALDH1A1 (0.56) ADRB2ADRB1ADRB3LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7384625-B2 Method and composition for rejuvenating hair, nails, tissues, cells and organs by ex-vivo or immersive treatment FARINGTON PHARMACEUTICALS, LLC (US) 2008-06-10 US disclosed
US-7022721-B1 Method and composition for rejuvenating cells, tissues, organs, hair and nails ULRICH PETER C 2006-04-04 US disclosed
US-20050245512-A1 Method and composition for rejuvinating cells, tissues organs, hair and nails ULRICH PETER C 2005-11-03 US disclosed
US-6777557-B2 Method and composition for rejuvenating cells, tissues organs, hair and nails FARRINGTON PHARMACEUTICALS, LLC 2004-08-17 US disclosed
US-6713050-B2 A THIAZOLIUM COMPOUND FOR TREATMENT OF HAIR, NAIL, EX-VIVO ORGAN, TISSUE OR CELLS BY IMPROVING THE DEFORMABILITY AND DIFFUSION COEFFICIENT OF HAIR, NAILS, TISSUES, CELLS, AND ORGANS IN HUMAN AND ANIMALS FARRINGTON PHARMACEUTICALS, INC. 2004-03-30 US disclosed
EP-0613677-B1 Nail enamels containing triol or glycol esters REVLON CONSUMER PROD CORP (US) 2001-07-04 EP disclosed
EP-0328585-B1 METABOLICALLY ACCEPTABLE POLYISOCYANATE ADHESIVES BIORESEARCH INC (US) 1994-09-07 EP disclosed
EP-0613677-A2 Nail enamels containing triol or glycol esters Revlon Consumer Products Corporation (US) 1994-09-07 EP disclosed
EP-0328585-A4 METABOLICALLY ACCEPTABLE POLYISOCYANATE ADHESIVES 1991-06-05 EP disclosed
EP-0328585-A1 METABOLICALLY ACCEPTABLE POLYISOCYANATE ADHESIVES BIORESEARCH INC. (US) 1989-08-23 EP disclosed
US-4829099-A SURGERY, POLYISOCYANATES, POLYISOTHIOCYANATES BIORESEARCH, INC. (US) 1989-05-09 US disclosed
WO-1989000589-A1 METABOLICALLY ACCEPTABLE POLYISOCYANATE ADHESIVES BIORESEARCH, INC. (US) 1989-01-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050245512-A1 Method and composition for rejuvinating cells, tissues organs, hair and nails TERT, TELO2, HKDC1 ADRB2 4593/4885ADRB1 4461/4885ADRB3 4246/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.