Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9420523 | 0.82 | APP (0.36) | GAAMAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL9420497 | 0.80 | CTSD (0.44) | ALDH1A1SMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL18393364 | 0.79 | SMN1; SMN2 (0.42) | GAAMAPTALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL9420519 | 0.78 | LMNA (0.32) | ALDH1A1SMN1; SMN2CYP3A4KDM4EKMT2A | |
| SCHEMBL9420487 | 0.77 | APP (0.43) | GAAMAPTALDH1A1TSHRNPC1 | |
| SCHEMBL9420508 | 0.77 | APP (0.43) | GAAMAPTALDH1A1TSHRNPC1 | |
| Hydrochloric Acid SCHEMBL9420482 | 0.74 | F2 (0.40) | ALDH1A1HSD17B10SMN1; SMN2NPC1KDM4E | |
| SCHEMBL9420490 | 0.73 | APP (0.39) | GAAMAPTALDH1A1TSHRNPC1 | |
| SCHEMBL7678490 | 0.71 | ALDH1A1 (0.59) | ALDH1A1HSD17B10SMN1; SMN2HPGDTSHR | |
| SCHEMBL6754011 | 0.71 | ALDH1A1 (0.41) | GAAMAPTALDH1A1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12623998-B2 | Process for preparing a polyisocyanate, polyisocyanate, its use and polyaddition products prepared therefrom | COVESTRO DEUTSCHLAND AG (DE) | 2026-05-12 | — | — | US | disclosed |
| US-20240018097-A1 | PROCESS FOR PREPARING A POLYISOCYANATE, POLYISOCYANATE, ITS USE AND POLYADDITION PRODUCTS PREPARED THEREFROM | COVESTRO DEUTSCHLAND AG (DE) | 2024-01-18 | — | — | US | disclosed |
| EP-4259685-A1 | PROCESS FOR PREPARING A POLYISOCYANATE, POLYISOCYANATE, ITS USE AND POLYADDITION PRODUCTS PREPARED THEREFROM | Covestro Deutschland AG (DE) | 2023-10-18 | — | — | EP | disclosed |
| CN-116568723-A | Process for preparing polyisocyanates, their use and polyaddition products made therefrom | 科思创德国股份有限公司 | 2023-08-08 | — | — | CN | disclosed |
| WO-2022122906-A1 | PROCESS FOR PREPARING A POLYISOCYANATE, POLYISOCYANATE, ITS USE AND POLYADDITION PRODUCTS PREPARED THEREFROM | COVESTRO DEUTSCHLAND AG (DE) | 2022-06-16 | — | — | WO | disclosed |
| EP-0328585-B1 | METABOLICALLY ACCEPTABLE POLYISOCYANATE ADHESIVES | BIORESEARCH INC (US) | 1994-09-07 | — | — | EP | disclosed |
| EP-0328585-A4 | METABOLICALLY ACCEPTABLE POLYISOCYANATE ADHESIVES | — | 1991-06-05 | — | — | EP | disclosed |
| EP-0328585-A1 | METABOLICALLY ACCEPTABLE POLYISOCYANATE ADHESIVES | BIORESEARCH INC. (US) | 1989-08-23 | — | — | EP | disclosed |
| US-4829099-A | SURGERY, POLYISOCYANATES, POLYISOTHIOCYANATES | BIORESEARCH, INC. (US) | 1989-05-09 | — | — | US | disclosed |
| WO-1989000589-A1 | METABOLICALLY ACCEPTABLE POLYISOCYANATE ADHESIVES | BIORESEARCH, INC. (US) | 1989-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12623998-B2 | Process for preparing a polyisocyanate, polyisocyanate, its use and polyaddition products prepared therefrom | PARG, AS3MT, PBRM1 | GAA 632/4885MAPT 3834/4885ALDH1A1 1808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.