Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2754953 | 0.86 | ALDH1A1 (0.39) | CYP3A4MAPTCYP1A2SMN1; SMN2TP53 | |
| SCHEMBL28335303 | 0.84 | PKM (0.49) | MAPTKDM4EPKM | |
| SCHEMBL4821864 | 0.84 | PKM (0.49) | MAPTKDM4EPKM | |
| SCHEMBL1673434 | 0.80 | CYP1A2 (0.34) | CYP3A4CYP1A2SMN1; SMN2TP53SLC6A2 | |
| SCHEMBL12292914 | 0.79 | CYP1A2 (0.46) | CYP3A4MAPTCYP1A2SMN1; SMN2KDM4E | |
| SCHEMBL31454831 | 0.79 | CYP1A2 (0.48) | CYP1A2MAOASLC6A2SLC6A3CYP2A6 | |
| SCHEMBL845625 | 0.79 | CYP1A2 (0.48) | CYP1A2MAOASLC6A2SLC6A3CYP2A6 | |
| Water SCHEMBL5596576 | 0.78 | ACHE (0.33) | CYP3A4CYP1A2SMN1; SMN2TP53SLC6A2 | |
| SCHEMBL7968031 | 0.78 | ALDH1A1 (0.61) | CYP3A4MAPTCYP1A2SMN1; SMN2LMNA | |
| SCHEMBL7968034 | 0.78 | ALDH1A1 (0.61) | CYP3A4MAPTCYP1A2SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286902-A | Process for preparation of 2-(6-methoxy-2-naphthyl)propionic acid and intermediates therefor utilizing 2,6-diisopropylnaphthalene | KOCH INDUSTRIES, INC. (US) | 1994-02-15 | — | — | US | disclosed |