Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | FLT1 | P17948 | 5/20 | 0.47 |
| ▸ | KDR | P35968 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9422978 | 0.88 | HTT (0.66) | HTTFLT1KDRALDH1A1MAPT | |
| SCHEMBL9423117 | 0.88 | HTT (0.52) | HTTFLT1KDRALDH1A1MAPT | |
| SCHEMBL8376590 | 0.88 | FLT1 (0.48) | HTTFLT1KDRALDH1A1MAPT | |
| SCHEMBL9423064 | 0.87 | MAPT (0.58) | HTTFLT1KDRALDH1A1MAPT | |
| SCHEMBL9423016 | 0.84 | PTGS2 (0.51) | HTTFLT1KDRALDH1A1MAPT | |
| SCHEMBL9423052 | 0.82 | HTT (0.48) | HTTALDH1A1MAPTLMNATP53 | |
| SCHEMBL8376535 | 0.77 | CRACR2A (0.40) | HTTKDRMAPTLMNACRACR2A | |
| SCHEMBL8487140 | 0.76 | HTT (0.43) | HTTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL8045733 | 0.75 | CRACR2A (0.51) | HTTFLT1KDRLMNATP53 | |
| SCHEMBL8817056 | 0.75 | MLYCD (0.41) | HTTALDH1A1MAPTLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371099-A | Antiinflammatory agents | ROUSSEL-UCLAF (FR) | 1994-12-06 | — | — | US | disclosed |