Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 2/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.35 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26976671 | 0.82 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1POLBCA2TYR | |
| Butylated Hydroxytoluene SCHEMBL8034258 | 0.81 | CA2 (0.82) | SMN1; SMN2ALDH1A1POLBCA2TYR | |
| Butylated Hydroxytoluene SCHEMBL11802507 | 0.76 | SMN1; SMN2 (0.72) | SMN1; SMN2ALDH1A1POLBCA2TYR | |
| SCHEMBL11357994 | 0.76 | POLB (0.46) | SMN1; SMN2ALDH1A1POLBCA2TYR | |
| SCHEMBL316288 | 0.75 | TSHR (0.50) | SMN1; SMN2ALDH1A1POLBCA2TYR | |
| SCHEMBL1655430 | 0.75 | GABRA1 (0.55) | SMN1; SMN2ALDH1A1POLBCA2TYR | |
| SCHEMBL15726917 | 0.74 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1POLBCA2TYR | |
| SCHEMBL2172272 | 0.73 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1POLBCA2TYR | |
| SCHEMBL29387025 | 0.73 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1POLBCA2TYR | |
| SCHEMBL10342450 | 0.73 | POLB (0.70) | SMN1; SMN2ALDH1A1POLBCA2TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592439-A1 | AMINOSULFONYL CARBAMATES | WARNER-LAMBERT COMPANY (US) | 1994-04-20 | — | — | EP | disclosed |
| WO-1992008693-A1 | AMINOSULFONYL CARBAMATES | WARNER-LAMBERT COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |