SCHEMBL2172272

SCHEMBL2172272

CC(C)(C)c1cc(O)c(-c2c(O)cc(C(C)(C)C)cc2C(C)(C)C)c(C(C)(C)C)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.50
ALOX15 P16050 5/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
CYP1A2 P05177 3/20 0.50
MAPT P10636 2/20 0.50
KDM4E B2RXH2 1/20 0.50
ATP2A2 P16615 1/20 0.50
ATP2A3 Q93084 1/20 0.50
TDP1 Q9NUW8 3/20 0.48
HSD17B10 Q99714 2/20 0.48
HPGD P15428 2/20 0.48
GABRA1 P14867 1/20 0.48
GABRB2 P47870 1/20 0.48
TYR P14679 3/20 0.41
LMNA P02545 3/20 0.41
CYP2C9 P11712 3/20 0.41
NR1I2 O75469 1/20 0.41
MIF P14174 1/20 0.41
HTT P42858 1/20 0.41
NFE2L2 Q16236 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29387025 1.00 ALDH1A1 (0.50) ALDH1A1ALOX15SMN1; SMN2CYP1A2MAPT
SCHEMBL29252780 0.94 ALDH1A1 (0.44) ALDH1A1ALOX15SMN1; SMN2CYP1A2MAPT
SCHEMBL29750737 0.94 ALDH1A1 (0.44) ALDH1A1ALOX15SMN1; SMN2CYP1A2MAPT
SCHEMBL14007404 0.85 GABRA1 (0.57) ALDH1A1ALOX15SMN1; SMN2CYP1A2MAPT
SCHEMBL29416834 0.81 CA2 (0.52) ALDH1A1ALOX15SMN1; SMN2CYP1A2MAPT
SCHEMBL247483 0.81 CA2 (0.52) ALDH1A1ALOX15SMN1; SMN2CYP1A2MAPT
SCHEMBL2293687 0.80 SHBG (0.46) ALDH1A1ALOX15SMN1; SMN2CYP1A2MAPT
SCHEMBL3618747 0.80 CNR1 (0.43) ALDH1A1ALOX15SMN1; SMN2CYP1A2MAPT
SCHEMBL30718926 0.79 CA2 (0.50) ALDH1A1ALOX15SMN1; SMN2CYP1A2MAPT
SCHEMBL29442064 0.79 ALDH1A1 (0.48) ALDH1A1ALOX15SMN1; SMN2CYP1A2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116947696-A Method for synthesizing adiponitrile by in-situ catalysis 刘凯凯 2023-10-27 CN claimed
CN-114835751-A Phosphite ester-phosphate ester compound and preparation method and application thereof 江西苏克尔新材料有限公司 2022-08-02 CN claimed
CN-114832860-A Olefin hydroformylation catalyst composition and preparation method and application thereof 江西苏克尔新材料有限公司 2022-08-02 CN claimed
EP-2346887-B1 SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES DOW TECHNOLOGY INVESTMENTS LLC (US) 2013-12-25 EP claimed
US-8546600-B2 Slurry process for synthesis of bisphosphites and situ use thereof for producing bisphosphite DOW TECHNOLOGY INVESTMENTS LLC 2013-10-01 US claimed
US-20110196166-A1 SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES AND SITU USE THEREOF FOR PRODUCING BISPHOSPHITE DOW TECHNOLOGY INVESTMENTS LLC 2011-08-11 US claimed
EP-2346887-A1 SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES Dow Technology Investments LLC (US) 2011-07-27 EP claimed
WO-2010042313-A1 SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES DOW TECHNOLOGY INVESTMENTS LLC (US) 2010-04-15 WO claimed
EP-1151986-B1 Method for removing tert-butyl groups from tert-butyl phenol compounds HONSHU CHEMICAL IND (JP) 2005-06-22 EP claimed
EP-1112993-B1 Process for producing 3,3',5,5'-tetra-t-butylbiphenol HONSHU CHEMICAL IND (JP) 2004-07-28 EP claimed
US-6512149-B2 Method for removing butyl groups from butyl phenol compounds HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2003-01-28 US claimed
US-20020007092-A1 Method for removing butyl groups from butyl phenol compounds HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2002-01-17 US claimed
EP-1151986-A1 Method for removing butyl groups from butyl phenol compounds Honshu Chemical Industry Co. Ltd. (JP) 2001-11-07 EP claimed
EP-0856504-B1 Process for producing 3,3',5,5'-tetra-t-butylbiphenol HONSHU CHEMICAL IND (JP) 2001-11-07 EP claimed
EP-1112993-A1 Process for producing 3,3',5,5'-tetra-t-butylbiphenol HONSHU CHEMICAL INDUSTRY CO. LTD. (JP) 2001-07-04 EP claimed
US-6118029-A Process for producing 3,3',5,5'-tetra-t butylbiphenol HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2000-09-12 US claimed
EP-0856504-A1 Process for producing 3,3',5,5'-tetra-t-butylbiphenol HONSHU CHEMICAL INDUSTRY CO. LTD. (JP) 1998-08-05 EP claimed
JP-10273460-A None JP disclosed
US-4482755-A High yield process for preparing 4,4'-biphenol and para-alkylbenzenes ICI AMERICAS INC. (US) 1984-11-13 US disclosed
JP-S58140034-A PREPARATION OF 3,5,3',5'-TETRA-TERT-BUTYLBIPHENOL SHOWA DENKO KK 1983-08-19 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110196166-A1 SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES AND SITU USE THEREOF FOR PRODUCING BISPHOSPHITE SOST, PLCB3, PPIP5K2 ALDH1A1 4653/4885ALOX15 2202/4885SMN1; SMN2 4334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.