Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | DHPS | P49366 | 11/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | METAP1 | P53582 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29770374 | 0.87 | DHPS (0.58) | DHPS | |
| SCHEMBL618135 | 0.87 | DHPS (0.58) | DHPS | |
| SCHEMBL7700308 | 0.85 | DHPS (0.51) | LMNADHPSL3MBTL1MEN1KMT2A | |
| SCHEMBL20665876 | 0.85 | METAP1 (0.57) | LMNAL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL6581656 | 0.83 | DHPS (0.52) | LMNADHPSFFAR1L3MBTL1MEN1 | |
| SCHEMBL9423634 | 0.83 | FFAR1 (0.51) | LMNAFFAR1L3MBTL1MEN1KMT2A | |
| SCHEMBL27715920 | 0.82 | LMNA (0.49) | LMNADHPSFFAR1MEN1KMT2A | |
| SCHEMBL7303389 | 0.79 | DHPS (0.81) | LMNADHPSMEN1KMT2AGAA | |
| SCHEMBL7795451 | 0.79 | DHPS (0.53) | DHPS | |
| SCHEMBL21741033 | 0.78 | METAP1 (0.50) | LMNAL3MBTL1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013057545-A1 | ACID ADDITION SALTS OF BOSENTAN | BIOCON LIMITED (IN) | 2013-04-25 | — | — | WO | disclosed |
| US-5292740-A | Sulfonamides | HOFFMANN-LA ROCHE INC. (US) | 1994-03-08 | — | — | US | disclosed |