SCHEMBL942452

SCHEMBL942452

Ic1cc2ccccc2c2ccccc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.55
GRIN2A Q12879 1/20 0.55
GRIN2C Q14957 1/20 0.55
ALDH1A1 P00352 5/20 0.52
HSD17B10 Q99714 4/20 0.52
HIF1A Q16665 2/20 0.52
CYP1B1 Q16678 1/20 0.52
TRPM4 Q8TD43 1/20 0.52
HPRT1 P00492 3/20 0.50
TSHR P16473 2/20 0.48
CYP2A6 P11509 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.42
PKM P14618 1/20 0.42
RAD52 P43351 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
CYP1A2 P05177 3/20 0.41
HPGD P15428 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9612411 0.83 GRIN2D (0.50) GRIN2DGRIN2AGRIN2CALDH1A1HSD17B10
SCHEMBL13706556 0.83 HPRT1 (0.64) GRIN2DGRIN2AGRIN2CALDH1A1HSD17B10
SCHEMBL18600582 0.81 CYP1A2 (0.50) GRIN2DGRIN2AGRIN2CALDH1A1HSD17B10
SCHEMBL17577289 0.81 CYP2A6 (0.43) GRIN2DGRIN2AGRIN2CALDH1A1HSD17B10
SCHEMBL2222869 0.80 GRIN2D (0.45) GRIN2DGRIN2AGRIN2CALDH1A1HSD17B10
SCHEMBL19802367 0.80 ALDH1A1 (0.67) GRIN2DGRIN2AGRIN2CALDH1A1HSD17B10
SCHEMBL16011864 0.79 GRIN2D (0.46) GRIN2DGRIN2AGRIN2CALDH1A1HSD17B10
SCHEMBL23096660 0.78 ALDH1A1 (0.46) GRIN2DGRIN2AGRIN2CALDH1A1HSD17B10
SCHEMBL10080502 0.78 GRIN2D (0.54) GRIN2DGRIN2AGRIN2CALDH1A1HSD17B10
SCHEMBL17702474 0.78 GRIN2D (0.54) GRIN2DGRIN2AGRIN2CALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118978510-A Preparation method, product and application of polydentate organic ligand and transition metal coordination polymer thereof 吉林大学 2024-11-19 CN claimed
US-7129008-B2 Holographic recording material LASER PHOTONICS TECHNOLOGY INC. (US) 2006-10-31 US claimed
US-6797745-B1 Hot melt inks containing styrene or terpene polymers XEROX CORPORATION 2004-09-28 US claimed
US-20040033423-A1 Holographic recording material LASER PHOTONICS TECHNOLOGY INC. 2004-02-19 US claimed
US-20020068225-A1 Holographic recording material LASER PHOTONICS TECHNOLOGY INC. 2002-06-06 US claimed
US-6344297-B1 POLYMERIZABLE ACRYLIC MONOMERS AND LIGHT ABSORBING PHENANTHRENEQUINONE DYES; SYMMETRIC CONCENTRATION DISTRIBUTION OF THE DYE LASER PHOTONICS TECHNOLOGY INC. 2002-02-05 US claimed
CN-118978510-A Preparation method, product and application of polydentate organic ligand and transition metal coordination polymer thereof 吉林大学 2024-11-19 CN disclosed
EP-4063368-B1 NITROGEN-CONTAINING COMPOUND AND ELECTRONIC ELEMENT COMPRISING SAME, AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MAT CO LTD (CN) 2024-06-26 EP disclosed
CN-117402276-A High-refraction cycloolefin copolymer and preparation method thereof 中国科学院长春应用化学研究所 2024-01-16 CN disclosed
WO-2023239091-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2023-12-14 WO disclosed
WO-2023239092-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2023-12-14 WO disclosed
US-20230348524-A1 TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION WAVE LIFE SCIENCES LTD. (SG) 2023-11-02 US disclosed
US-20230309381-A1 AMINE COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-28 US disclosed
US-5260461-A Asymmetric dihydroxylation of olefins, osmium tetraoxide stereoselective catalyst, enantiomers, ferricyanide salt MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1993-11-09 US disclosed
US-5227543-A Assymetric dihydroxylation of olefins MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1993-07-13 US disclosed
EP-0543969-A1 HETEROCYCLIC CHIRAL LIGANDS AND METHOD FOR CATALYTIC ASYMMETRIC DIHYDROXYLATION OF OLEFINS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1993-06-02 EP disclosed
WO-1993007142-A1 NEW LIGANDS FOR ASYMMETRIC DIHYDROXYLATION: MULTIPLE CINCHONA ALKALOID UNITS ATTACHED TO A CENTRAL HETEROCYCLIC CORE MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1993-04-15 WO disclosed
EP-0526582-A1 HETEROCYCLIC CHIRAL LIGANDS AND METHOD FOR CATALYTIC ASYMMETRIC DIHYDROXYLATION OF OLEFINS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1993-02-10 EP disclosed
WO-1992020677-A1 HETEROCYCLIC CHIRAL LIGANDS AND METHOD FOR CATALYTIC ASYMMETRIC DIHYDROXYLATION OF OLEFINS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1992-11-26 WO disclosed
WO-1991016322-A2 HETEROCYCLIC CHIRAL LIGANDS AND METHOD FOR CATALYTIC ASYMMETRIC DIHYDROXYLATION OF OLEFINS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1991-10-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348524-A1 TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION POLRMT, DCLRE1B, RNGTT GRIN2D 4876/4885GRIN2A 4832/4885GRIN2C 4873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.