Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9424464 | 0.90 | KMT2A (0.47) | ALDH1A1KMT2AMEN1KLKB1CTSB | |
| SCHEMBL9424478 | 0.89 | KMT2A (0.48) | ALDH1A1KMT2AMEN1KLKB1CTSB | |
| SCHEMBL9424731 | 0.80 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1HTTNFKB1 | |
| SCHEMBL9424721 | 0.79 | MAPT (0.58) | ALDH1A1KMT2AMEN1HTTLMNA | |
| SCHEMBL9424582 | 0.79 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1KLKB1CTSB | |
| SCHEMBL9424517 | 0.79 | KMT2A (0.47) | ALDH1A1KMT2AMEN1KLKB1CTSB | |
| SCHEMBL9424699 | 0.78 | EPHX1 (0.48) | ALDH1A1KMT2AMEN1HTTLMNA | |
| SCHEMBL9424328 | 0.77 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1KLKB1CTSB | |
| SCHEMBL9424446 | 0.77 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1HTTLMNA | |
| SCHEMBL9424554 | 0.76 | EPHX1 (0.49) | ALDH1A1KMT2AMEN1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5302724-A | Thiophenesulfonylureas; anticarcinogenic agents | ELI LILLY AND COMPANY (US) | 1994-04-12 | — | — | US | disclosed |
| EP-0467613-A1 | Antitumor compositions and methods of treatment | ELI LILLY AND COMPANY (US) | 1992-01-22 | — | — | EP | disclosed |