Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9425245 | 0.88 | LMNA (0.40) | LMNAMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL3904725 | 0.80 | ALOX5 (0.36) | LMNAMAPTALDH1A1KMT2ARAB9A | |
| SCHEMBL9424969 | 0.80 | CDK2 (0.35) | LMNAMAPTALDH1A1RAB9ACDK2 | |
| SCHEMBL9424861 | 0.73 | LMNA (0.42) | LMNAMAPTALDH1A1KMT2AHPGD | |
| SCHEMBL3899379 | 0.73 | ALOX5 (0.35) | LMNAMAPTALDH1A1KMT2ARAB9A | |
| Hydrochloric Acid SCHEMBL3903344 | 0.69 | KMT2A (0.35) | LMNAMAPTALDH1A1KMT2ACDK2 | |
| SCHEMBL3907883 | 0.69 | ACHE (0.35) | MAPTALDH1A1KMT2AMEN1HTT | |
| SCHEMBL3907421 | 0.69 | L3MBTL1 (0.36) | LMNAMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL3899292 | 0.67 | ACHE (0.34) | MAPTHTT | |
| SCHEMBL3968959 | 0.67 | MAPT (0.31) | MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5290936-A | Indicators or labels for antibodies or medical diagnosis | LONDON DIAGNOSTICS, INC. (US) | 1994-03-01 | — | — | US | disclosed |
| US-5284951-A | Aryl ester, thioester or amide of carboxylic acid substituted heterocyclic ring; quaternary compounds | LONDON DIAGNOSTICS, INC. (US) | 1994-02-08 | — | — | US | disclosed |
| US-5283334-A | Side-chain functional chemiluminescent labels and their conjugates, and assays therefrom | LONDON DIAGNOSTICS, INC. (US) | 1994-02-01 | — | — | US | disclosed |