Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.41 |
| ▸ | USP8 | P40818 | 1/20 | 0.39 |
| ▸ | USP7 | Q93009 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9424690 | 0.80 | KDM4E (0.44) | KDM4ETUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7698174 | 0.76 | PDE3B (0.47) | KDM4EPDE3BPDE3AALOX15KMT2A | |
| SCHEMBL28757799 | 0.70 | CA12 (0.42) | KDM4EPDE3BPDE3AALOX15KMT2A | |
| SCHEMBL7702486 | 0.69 | ALOX15 (0.57) | KDM4EALOX15KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL9424875 | 0.67 | NUDT1 (0.56) | SRCEGFRSMN1; SMN2 | |
| SCHEMBL31353608 | 0.67 | SMN1; SMN2 (0.44) | SRCKDM4ENSD2KMT2ASMN1; SMN2 | |
| SCHEMBL8643555 | 0.66 | GABRA1 (0.43) | KDM4EPDE3BPDE3AKMT2ASMN1; SMN2 | |
| SCHEMBL8495848 | 0.65 | ALDH1A1 (0.47) | KDM4EPDE3BPDE3AEGFRKMT2A | |
| SCHEMBL2910842 | 0.65 | ALOX15 (0.56) | KDM4EPDE3BPDE3AALOX15KMT2A | |
| SCHEMBL16038264 | 0.65 | WHR1 (0.47) | KDM4EPDE3BPDE3AALOX15POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5318963-A | Heterocyclic hydrazide derivatives of monocyclic β-lactam antibiotics | E. R. SQUIBB & SONS, INC. (US) | 1994-06-07 | — | — | US | disclosed |
| EP-0420069-A2 | Heterocyclic hydrazide derivatives of monocyclic beta-lactam antibiotics | E.R. SQUIBB & SONS, INC. (US) | 1991-04-03 | — | — | EP | disclosed |