Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 3/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 3/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.34 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.33 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9425916 | 0.85 | CA12 (0.34) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9425798 | 0.81 | RXRB (0.50) | XDHSLC22A12RXRBAKR1C2AKR1C1 | |
| SCHEMBL5667262 | 0.76 | ACMSD (0.46) | XDHSLC22A12RXRBRXRAMCL1 | |
| SCHEMBL9425911 | 0.75 | HSD17B1 (0.37) | — | |
| SCHEMBL1095325 | 0.73 | ACMSD (0.58) | XDHSLC22A12MCL1DCLRE1ADCLRE1B | |
| SCHEMBL9425970 | 0.72 | RXRB (0.58) | XDHSLC22A12RXRBAKR1C2AKR1C1 | |
| SCHEMBL9425673 | 0.72 | NPC1 (0.37) | NPC1RAB9ASMN1; SMN2RARBFFAR4 | |
| Hydrochloric Acid SCHEMBL4352423 | 0.72 | ACMSD (0.56) | XDHSLC22A12MCL1DCLRE1ADCLRE1B | |
| SCHEMBL5666966 | 0.72 | TDP1 (0.41) | RXRBAKR1C2AKR1C1RXRARARB | |
| SCHEMBL8960093 | 0.70 | PTPN1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5349105-A | Skin disorder | ALLERGAN, INC. (US) | 1994-09-20 | — | — | US | disclosed |
| US-5202471-A | Skin disorders | ALLERGAN, INC. (US) | 1993-04-13 | — | — | US | disclosed |