Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9425658 | 0.84 | HSD17B1 (0.43) | HSD17B1CNR1 | |
| SCHEMBL9425673 | 0.83 | NPC1 (0.37) | — | |
| SCHEMBL9426099 | 0.80 | RARB (0.39) | HSD17B1 | |
| SCHEMBL9425916 | 0.77 | CA12 (0.34) | CNR2 | |
| SCHEMBL9425231 | 0.76 | RXRB (0.46) | HSD17B1 | |
| SCHEMBL9425670 | 0.75 | XDH (0.38) | — | |
| SCHEMBL8866201 | 0.66 | HDAC3 (0.39) | HSD17B1 | |
| SCHEMBL9116437 | 0.65 | HSD17B1 (0.35) | HSD17B1 | |
| SCHEMBL2849373 | 0.64 | CES2 (0.42) | SRD5A2 | |
| SCHEMBL8960093 | 0.64 | PTPN1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5349105-A | Skin disorder | ALLERGAN, INC. (US) | 1994-09-20 | — | — | US | disclosed |
| US-5202471-A | Skin disorders | ALLERGAN, INC. (US) | 1993-04-13 | — | — | US | disclosed |