Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 3/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17876912 | 0.89 | LMNA (0.39) | LMNAF10F2HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL17866611 | 0.86 | LMNA (0.43) | LMNAF10F2HTR3EHTR3B | |
| SCHEMBL9426187 | 0.74 | PRSS1 (0.46) | LMNA | |
| Hydrochloric Acid SCHEMBL9426233 | 0.72 | PRSS1 (0.45) | LMNA | |
| SCHEMBL9425946 | 0.69 | PRSS1 (0.42) | CCR1CCR5CCR8F10F2 | |
| SCHEMBL2723616 | 0.68 | ALDH1A1 (0.46) | LMNAHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL29363452 | 0.68 | ALDH1A1 (0.46) | LMNAHTR3EHTR3BHTR3AHTR3D | |
| Hydrochloric Acid SCHEMBL4333376 | 0.67 | ALDH1A1 (0.45) | LMNAHTR3EHTR3BHTR3AHTR3D | |
| Hydrochloric Acid SCHEMBL31708318 | 0.67 | ALDH1A1 (0.45) | LMNAHTR3EHTR3BHTR3AHTR3D | |
| Hydrochloric Acid SCHEMBL9375514 | 0.66 | CNR2 (0.55) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354761-A | Antiprotozoa agents | CIBA-GEIGY CORP. (US) | 1994-10-11 | — | — | US | disclosed |
| EP-0495749-A1 | Bipyridines | CIBA-GEIGY AG (CH) | 1992-07-22 | — | — | EP | disclosed |