Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.46 |
| ▸ | C1S | P09871 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 3/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9426233 | 0.98 | PRSS1 (0.45) | PRSS1PRSS2PRSS3C1SNOS1 | |
| SCHEMBL24121412 | 0.89 | PRSS1 (0.52) | PRSS1PRSS2PRSS3C1SNOS1 | |
| Hydrochloric Acid SCHEMBL5729538 | 0.81 | NOS3 (0.45) | PRSS1PRSS2PRSS3C1SNOS1 | |
| SCHEMBL9426333 | 0.78 | LMNA (0.48) | KDM4EALDH1A1LMNAGAA | |
| SCHEMBL9425286 | 0.78 | BAZ2B (0.33) | PRSS1PRSS2PRSS3C1SNOS1 | |
| SCHEMBL9425718 | 0.75 | NOS3 (0.32) | PRSS1PRSS2PRSS3C1SNOS3 | |
| SCHEMBL9425438 | 0.75 | CCR1 (0.31) | PRSS1PRSS2PRSS3C1SNOS1 | |
| SCHEMBL9425796 | 0.74 | LMNA (0.35) | LMNA | |
| SCHEMBL9425946 | 0.74 | PRSS1 (0.42) | PRSS1PRSS2PRSS3C1SPLAU | |
| SCHEMBL8153950 | 0.68 | PLAU (0.48) | PRSS1PRSS2PRSS3C1SNOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354761-A | Antiprotozoa agents | CIBA-GEIGY CORP. (US) | 1994-10-11 | — | — | US | claimed |
| EP-0495749-A1 | Bipyridines | CIBA-GEIGY AG (CH) | 1992-07-22 | — | — | EP | claimed |
| JP-4312576-A | — | — | None | — | — | JP | disclosed |
| JP-H04312576-A | BIPYRDYL | CIBA GEIGY AG | 1992-11-04 | — | — | JP | disclosed |