Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.42 |
| ▸ | PLAU | P00749 | 3/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PTGIR | P43119 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9426187 | 0.74 | PRSS1 (0.46) | PRSS1PRSS2PRSS3PLAUALDH1A1 | |
| Hydrochloric Acid SCHEMBL9426233 | 0.72 | PRSS1 (0.45) | PRSS1PRSS2PRSS3PLAUALDH1A1 | |
| SCHEMBL14266624 | 0.72 | NOS3 (0.53) | PRSS1PRSS2PRSS3PLAUPTGIR | |
| SCHEMBL29435763 | 0.72 | NOS3 (0.53) | PRSS1PRSS2PRSS3PLAUPTGIR | |
| Hydrochloric Acid SCHEMBL31037743 | 0.70 | NOS3 (0.52) | PRSS1PRSS2PRSS3PLAUALDH1A1 | |
| Hydrochloric Acid SCHEMBL17893837 | 0.70 | NOS3 (0.52) | PRSS1PRSS2PRSS3PLAUALDH1A1 | |
| SCHEMBL5223539 | 0.69 | LMNA (0.48) | PLAUALDH1A1 | |
| SCHEMBL9425796 | 0.69 | LMNA (0.35) | CCR1CCR5CCR8F10F2 | |
| Caerulomycinamide SCHEMBL8513634 | 0.69 | HSP90AA1 (0.55) | ALDH1A1HSP90AA1F2CYP3A4 | |
| SCHEMBL3368246 | 0.69 | PRSS1 (0.64) | PRSS1PRSS2PRSS3PLAUPLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354761-A | Antiprotozoa agents | CIBA-GEIGY CORP. (US) | 1994-10-11 | — | — | US | claimed |
| EP-0495749-A1 | Bipyridines | CIBA-GEIGY AG (CH) | 1992-07-22 | — | — | EP | claimed |
| US-5354761-A | Antiprotozoa agents | CIBA-GEIGY CORP. (US) | 1994-10-11 | — | — | US | disclosed |
| EP-0495749-A1 | Bipyridines | CIBA-GEIGY AG (CH) | 1992-07-22 | — | — | EP | disclosed |