Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CD44 | P16070 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.31 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29634741 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CYP1A2ALOX15CASP7HIF1A | |
| Hydrochloric Acid SCHEMBL7861016 | 0.98 | ALDH1A1 (0.48) | ALDH1A1CYP1A2ALOX15CASP7HIF1A | |
| Hydrochloric Acid SCHEMBL7861014 | 0.98 | ALDH1A1 (0.48) | ALDH1A1CYP1A2ALOX15CASP7HIF1A | |
| SCHEMBL5694433 | 0.91 | ALDH1A1 (0.61) | ALDH1A1CYP1A2ALOX15CASP7HIF1A | |
| SCHEMBL6575833 | 0.83 | ALDH1A1 (0.38) | ALDH1A1CYP1A2ALOX15CASP7HIF1A | |
| SCHEMBL23642752 | 0.82 | ALDH1A1 (0.67) | ALDH1A1CYP1A2ALOX15CASP7HIF1A | |
| SCHEMBL3342948 | 0.82 | ALDH1A1 (0.41) | ALDH1A1CYP1A2ALOX15CASP7HIF1A | |
| SCHEMBL29265971 | 0.81 | PTK2 (0.42) | ALDH1A1CYP1A2ALOX15CASP7HIF1A | |
| SCHEMBL16932994 | 0.79 | ALDH1A1 (0.37) | ALDH1A1CYP1A2ALOX15CASP7HIF1A | |
| SCHEMBL31265135 | 0.77 | TYR (0.41) | ALDH1A1ALOX15CYP3A4TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 424 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023054558-A1 | COMPOSITION COMPRISING A DYE AND INORGANIC ALKALIZING AGENT | KAO CORPORATION (JP) | 2023-04-06 | — | — | WO | claimed |
| EP-4159184-A1 | COMPOSITION COMPRISING A DYE AND INORGANIC ALKALIZING AGENT | Kao Corporation (JP) | 2023-04-05 | — | — | EP | claimed |
| EP-2658507-B1 | OXIDATIVE COLOURING COMPOSITION | KAO GERMANY GMBH (DE) | 2019-04-24 | — | — | EP | claimed |
| US-8613778-B2 | Oxidative colouring composition | KAO GERMANY GMBH (DE) | 2013-12-24 | — | — | US | claimed |
| EP-2658507-A1 | OXIDATIVE COLOURING COMPOSITION | Kao Germany GmbH (DE) | 2013-11-06 | — | — | EP | claimed |
| US-20130276811-A1 | OXIDATIVE COLOURING COMPOSITION | KAO GERMANY GMBH (DE) | 2013-10-24 | — | — | US | claimed |
| WO-2012089648-A1 | OXIDATIVE COLOURING COMPOSITION | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2012-07-05 | — | — | WO | claimed |
| EP-2468241-A1 | Oxidative colouring composition | KPSS-Kao Professional Salon Services GmbH (DE) | 2012-06-27 | — | — | EP | claimed |
| EP-1598049-B1 | Composition for coloring of keratin fibres | KPSS KAO GMBH (DE) | 2008-08-06 | — | — | EP | claimed |
| EP-1250908-B1 | Hair dye | KPSS KAO GMBH (DE) | 2007-03-14 | — | — | EP | claimed |
| US-20050257332-A1 | Composition for coloring of keratin fibres | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2005-11-24 | — | — | US | claimed |
| EP-1598049-A1 | Composition for coloring of keratin fibres | KPSS-Kao Professional Salon Services GmbH (DE) | 2005-11-23 | — | — | EP | claimed |
| EP-1297818-A2 | Hair dye | KPSS-Kao Professional Salon Services GmbH (DE) | 2003-04-02 | — | — | EP | claimed |
| EP-1250908-A2 | Hair dye | GOLDWELL GmbH (DE) | 2002-10-23 | — | — | EP | claimed |
| EP-0911317-B1 | Process for the preparation of 2-hydroyalkyl paraphenylenediamines, novel 2-hydroxyalkyl paraphenylenediamines, their use for oxydative dyeing, dye compositions and dyeing processes | OREAL (FR) | 2000-09-13 | — | — | EP | claimed |
| EP-0911317-A1 | Process for the preparation of 2-hydroyalkyl paraphenylenediamines, novel 2-hydroxyalkyl paraphenylenediamines, their use for oxydative dyeing, dye compositions and dyeing processes | L'OREAL (FR) | 1999-04-28 | — | — | EP | claimed |
| EP-2658508-B2 | TWO-PART HAIR COLOURING COMPOSITION | KAO GERMANY GMBH (DE) | 2024-06-19 | — | — | EP | disclosed |
| EP-3427720-B1 | AQUEOUS BLEACHING AND/OR DYEING COMPOSITION FOR KERATIN FIBERS, PROCESS, KIT AND USE THEREOF | KAO GERMANY GMBH (DE) | 2024-05-22 | — | — | EP | disclosed |
| EP-0911317-B1 | Process for the preparation of 2-hydroyalkyl paraphenylenediamines, novel 2-hydroxyalkyl paraphenylenediamines, their use for oxydative dyeing, dye compositions and dyeing processes | OREAL (FR) | 2000-09-13 | — | — | EP | disclosed |
| EP-0911317-A1 | Process for the preparation of 2-hydroyalkyl paraphenylenediamines, novel 2-hydroxyalkyl paraphenylenediamines, their use for oxydative dyeing, dye compositions and dyeing processes | L'OREAL (FR) | 1999-04-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050257332-A1 | Composition for coloring of keratin fibres | KRT18, CBR3, CYC1 | ALDH1A1 299/4885CYP1A2 537/4885ALOX15 2819/4885 |
| US-20130276811-A1 | OXIDATIVE COLOURING COMPOSITION | KRT18, MT-ND5, MT-CO1 | ALDH1A1 546/4885CYP1A2 973/4885ALOX15 1581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.