Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRB | P28702 | 6/20 | 0.62 |
| ▸ | RXRA | P19793 | 5/20 | 0.62 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21448425 | 0.82 | RXRA (0.69) | RXRBRXRAKIF11RXRGEGFR | |
| SCHEMBL9425231 | 0.81 | RXRB (0.46) | RXRBRXRAKIF11DHODHACHE | |
| SCHEMBL13422461 | 0.77 | RXRB (1.00) | RXRBRXRAKIF11RXRGDHODH | |
| SCHEMBL13524610 | 0.77 | RXRB (0.76) | RXRBRXRAKIF11RXRGDHODH | |
| SCHEMBL3587908 | 0.76 | RXRA (0.73) | RXRBRXRAKIF11RXRGDHODH | |
| SCHEMBL2746989 | 0.76 | KMO (0.49) | RXRBRXRARXRGDHODHEGFR | |
| SCHEMBL1713017 | 0.73 | ELANE (0.40) | — | |
| SCHEMBL27659191 | 0.73 | KIF11 (0.76) | RXRBRXRAKIF11RXRGDHODH | |
| SCHEMBL17105790 | 0.71 | KIF11 (0.68) | RXRBRXRAKIF11DHODHHDAC8 | |
| SCHEMBL30023786 | 0.71 | KIF11 (0.72) | RXRBRXRAKIF11ACHEHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5349105-A | Skin disorder | ALLERGAN, INC. (US) | 1994-09-20 | — | — | US | disclosed |
| US-5202471-A | Skin disorders | ALLERGAN, INC. (US) | 1993-04-13 | — | — | US | disclosed |