Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29017996 | 0.79 | CA12 (0.31) | TDP1 | |
| SCHEMBL12960880 | 0.77 | MMP1 (0.39) | CTSAACHESMPD1KDM4ETDP1 | |
| SCHEMBL2160083 | 0.72 | PGD (0.31) | — | |
| SCHEMBL1840428 | 0.72 | PGK1 (0.38) | SMPD1KDM4ETDP1 | |
| SCHEMBL183389 | 0.72 | SMPD1 (0.34) | CTSAACHESMPD1TDP1 | |
| SCHEMBL19281218 | 0.72 | PGK1 (0.38) | SMPD1KDM4ETDP1 | |
| SCHEMBL9952548 | 0.72 | PGK1 (0.38) | SMPD1KDM4ETDP1 | |
| Ammonia Solution, Strong SCHEMBL28328876 | 0.70 | SMPD1 (0.33) | SMPD1TDP1 | |
| SCHEMBL11522192 | 0.70 | CA4 (0.40) | SMPD1TDP1 | |
| SCHEMBL26913628 | 0.70 | PGK1 (0.37) | SMPD1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5302393-A | Method for inhibiting biological degradation of implantation polymeric material, inhibitor thereof and implantation polymeric material containing the inhibitor | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1994-04-12 | — | — | US | disclosed |
| EP-0523555-A1 | Pharmaceutical composition useful in inhibiting biological degradation of polymeric implantation material | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1993-01-20 | — | — | EP | disclosed |