SCHEMBL1840428

SCHEMBL1840428

CC(OP(=O)(O)O)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 1/20 0.38
PGK2 P07205 1/20 0.38
LAP3 P28838 2/20 0.37
TP53 P04637 1/20 0.36
PGD P52209 1/20 0.35
SMPD1 P17405 3/20 0.34
KDM4E B2RXH2 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19281218 1.00 PGK1 (0.38) PGK1PGK2LAP3TP53PGD
SCHEMBL9952548 1.00 PGK1 (0.38) PGK1PGK2LAP3TP53PGD
SCHEMBL27241907 0.97 PGK1 (0.37) PGK1PGK2LAP3TP53PGD
SCHEMBL26913628 0.97 PGK1 (0.37) PGK1PGK2LAP3TP53PGD
SCHEMBL23931184 0.95 PGK1 (0.35) PGK1PGK2LAP3TP53PGD
SCHEMBL183389 0.79 SMPD1 (0.34) PGK1PGK2SMPD1TDP1
SCHEMBL8416620 0.78 PEPD (0.43) PGK1PGK2LAP3SMPD1KDM4E
SCHEMBL11522192 0.77 CA4 (0.40) LAP3PGDSMPD1TDP1
Ammonia Solution, Strong SCHEMBL28328876 0.77 SMPD1 (0.33) PGK1PGK2SMPD1TDP1
SCHEMBL12257190 0.77 LAP3 (0.44) LAP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107075588-B Methods and systems for microbiome-derived diagnosis and treatment 普梭梅根公司 2023-03-21 CN claimed
CN-105136877-B The preparation method of people's odor-binding protein sensor of nanohole array and application 浙江大学 2018-06-22 CN claimed
CN-107334022-A A kind of preparation method rich in the former wine drink of beta glucan 李辉 2017-11-10 CN claimed
EP-2872514-B1 IMIDAZOTRIAZINECARBONITRILES USEFUL AS KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2017-08-30 EP claimed
US-9273057-B2 Imidazotriazinecarbonitriles useful as kinase inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2016-03-01 US claimed
US-20140080788-A1 NOVEL BICYCLIC NITROGEN CONTAINING HETEROARYL TGR5 RECEPTOR MODULATORS BRISTOL-MYERS SQUIBB COMPANY 2014-03-20 US claimed
EP-1019418-B1 INOSITOL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM BIONERIS AB (SE) 2004-04-28 EP claimed
US-20250082595-A1 METHODS AND COMPOSITIONS FOR TREATING PARKINSON’S DISEASE NEURODERM LTD (IL) 2025-03-13 US disclosed
US-20240315997-A1 METHOD OF TREATMENT OF PARKINSON’S DISEASE NEURODERM, LTD. (IL) 2024-09-26 US disclosed
US-11844754-B2 Methods for treatment of Parkinson's disease NEURODERM, LTD. (IL) 2023-12-19 US disclosed
WO-2023195753-A1 BUILDING INTERIOR AND EXTERIOR COMPOSITE INSULATION MATERIAL WITH SEMI-NONCOMBUSTIBLE PERFORMANCE, EXCELLENT FLAME RETARDANCY AND MOISTURE PROOF PERFORMANCE, AND ENHANCED ENERGY EFFICIENCY 삼우에스엔씨코 주식회사 2023-10-12 WO disclosed
US-20230157985-A1 METHODS FOR TREATMENT OF PARKINSON'S DISEASE NEURODERM, LTD. (IL) 2023-05-25 US disclosed
CN-107075588-B Methods and systems for microbiome-derived diagnosis and treatment 普梭梅根公司 2023-03-21 CN disclosed
EP-1019418-A1 A NEW CHEMICAL COMPOUND PERSTORP AB (SE) 2000-07-19 EP disclosed
EP-1012298-A1 YEAST STRAINS FOR THE PRODUCTION OF LACTIC ACID A.E. STALEY MANUFACTURING COMPANY (US) 2000-06-28 EP disclosed
WO-1999014335-A1 YEAST STRAINS FOR THE PRODUCTION OF LACTIC ACID A.E. STALEY MANUFACTURING COMPANY (US) 1999-03-25 WO disclosed
EP-0857203-A2 METHODS AND COMPOSITIONS TO IMPROVE GERM CELL AND EMBRYO SURVIVAL AND FUNCTION Advanced Reproduction Technologies, Inc. (US) 1998-08-12 EP disclosed
WO-1997026266-A1 A NEW CHEMICAL COMPOUND PERSTORP AB (SE) 1997-07-24 WO disclosed
WO-1997014785-A2 METHODS AND COMPOSITIONS TO IMPROVE GERM CELL AND EMBRYO SURVIVAL AND FUNCTION ADVANCED REPRODUCTION TECHNOLOGIES, INC. (US) 1997-04-24 WO disclosed
EP-0192113-B1 Cationic coating compositions for electrodeposition over rough steel PPG INDUSTRIES INC (US) 1995-10-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11844754-B2 Methods for treatment of Parkinson's disease DDC, DDT, SLC6A3 PGK1 3077/4885PGK2 2597/4885LAP3 94/4885
US-20140080788-A1 NOVEL BICYCLIC NITROGEN CONTAINING HETEROARYL TGR5 RECEPTOR MODULATORS GRK5, GPBAR1, GPR55 PGK1 2114/4885PGK2 2042/4885LAP3 3152/4885
US-20240315997-A1 METHOD OF TREATMENT OF PARKINSON’S DISEASE DDC, DDT, COMT PGK1 2958/4885PGK2 2512/4885LAP3 102/4885
US-20250082595-A1 METHODS AND COMPOSITIONS FOR TREATING PARKINSON’S DISEASE DDC, COMT, DDT PGK1 3197/4885PGK2 2646/4885LAP3 163/4885
US-20230157985-A1 METHODS FOR TREATMENT OF PARKINSON'S DISEASE DDC, DDT, COMT PGK1 3059/4885PGK2 2577/4885LAP3 93/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.