Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | PARG | Q86W56 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19808139 | 0.77 | ALDH1A1 (0.36) | MEN1KMT2AGAAALDH1A1PARG | |
| SCHEMBL22648437 | 0.76 | ALDH1A1 (0.57) | KMT2AALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL9426501 | 0.76 | NSD2 (0.45) | MEN1KMT2AGAAALDH1A1PARG | |
| SCHEMBL19808142 | 0.73 | GAA (0.34) | MEN1KMT2AGAAALDH1A1PARG | |
| SCHEMBL9426240 | 0.71 | TSHR (0.34) | MEN1KMT2AGAAALDH1A1PARG | |
| SCHEMBL9426521 | 0.71 | GAA (0.54) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL634086 | 0.71 | CA1 (0.57) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL2616314 | 0.69 | MGLL (0.42) | GAAALDH1A1MAPTL3MBTL1TSHR | |
| SCHEMBL9917355 | 0.69 | RIPK1 (0.43) | — | |
| SCHEMBL12780470 | 0.64 | PSIP1 (0.43) | GAAALDH1A1HPGDSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356862-A | Herbicidal sulfonylureas | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-10-18 | — | — | US | disclosed |
| EP-0511993-A1 | HERBICIDAL SULFONYLUREAS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-11-11 | — | — | EP | disclosed |
| WO-1991010668-A1 | HERBICIDAL SULFONYLUREAS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-07-25 | — | — | WO | disclosed |