Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL94275 | 0.89 | HTR2A (0.52) | HTR2ATAAR1HRH1TDP1CHRNB2 | |
| SCHEMBL7429108 | 0.76 | IDO1 (0.50) | HTR2ATAAR1TDP1CHRNB2CHRNA4 | |
| SCHEMBL7430169 | 0.76 | CYP19A1 (0.44) | HTR2ATAAR1HRH1CHRNB2CHRNA4 | |
| SCHEMBL4244702 | 0.74 | ALDH1A1 (0.43) | TDP1TSHRLMNA | |
| SCHEMBL19 | 0.74 | — | — | |
| SCHEMBL4892666 | 0.74 | CES2 (0.42) | HTR2ATAAR1HRH1DPP4F2 | |
| SCHEMBL8322755 | 0.72 | KIF11 (0.41) | HTR2ATAAR1HRH1TDP1LMNA | |
| SCHEMBL17351648 | 0.72 | SLC6A2 (0.49) | — | |
| SCHEMBL7411961 | 0.72 | ACP3 (0.53) | TDP1RAB9ALMNA | |
| SCHEMBL8324166 | 0.72 | ACP3 (0.47) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736026-A1 | NEW PYRIDAZINO 4',5':3,4]PYRROLO- 2,1-A]ISOQUINOLINES AND THEIR USE FOR PREPARING PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM KG (DE) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995017402-A1 | NEW PYRIDAZINO[4',5':3,4]PYRROLO-[2,1-A]ISOQUINOLINES AND THEIR USE FOR PREPARING PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM KG (DE) | 1995-06-29 | — | — | WO | disclosed |