Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9427781 | 0.85 | RAB9A (0.57) | RAB9ANPC1ALOX5SMN1; SMN2TP53 | |
| SCHEMBL9472171 | 0.83 | RAB9A (0.66) | RAB9ANPC1ALOX5SMN1; SMN2TP53 | |
| Water SCHEMBL9427943 | 0.82 | RAB9A (0.62) | RAB9ANPC1ALOX5SMN1; SMN2TP53 | |
| SCHEMBL9428765 | 0.77 | ALOX5 (0.49) | ALOX5PDE10A | |
| SCHEMBL9428008 | 0.77 | NPC1 (0.53) | RAB9ANPC1ALOX5SMN1; SMN2MEN1 | |
| SCHEMBL9503988 | 0.76 | RAB9A (0.53) | RAB9ANPC1ALOX5SMN1; SMN2TP53 | |
| SCHEMBL4725005 | 0.75 | RAB9A (0.75) | RAB9ANPC1SMN1; SMN2TP53PDE10A | |
| SCHEMBL9584450 | 0.74 | RAB9A (0.59) | RAB9ANPC1ALOX5SMN1; SMN2TP53 | |
| SCHEMBL2247920 | 0.74 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2TP53MEN1 | |
| SCHEMBL7713248 | 0.73 | ALOX5 (0.78) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364944-A | Antiinflammatory, antiallergic and cytoprotective agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-11-15 | — | — | US | disclosed |
| US-5218124-A | Antiinflammatory agents, antiallergens and cytoprotective agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-06-08 | — | — | US | disclosed |