Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.55 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 4/20 | 0.52 |
| ▸ | CES1 | P23141 | 4/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.50 |
| ▸ | PPARG | P37231 | 7/20 | 0.50 |
| ▸ | PPARD | Q03181 | 7/20 | 0.50 |
| ▸ | PPARA | Q07869 | 7/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4329016 | 1.00 | SPHK2 (0.55) | SPHK2SPHK1CES2CES1GPR84 | |
| SCHEMBL7611635 | 1.00 | SPHK2 (0.55) | SPHK2SPHK1CES2CES1GPR84 | |
| SCHEMBL7513495 | 1.00 | SPHK2 (0.55) | SPHK2SPHK1CES2CES1GPR84 | |
| SCHEMBL7519082 | 1.00 | SPHK2 (0.55) | SPHK2SPHK1CES2CES1GPR84 | |
| SCHEMBL608431 | 1.00 | SPHK2 (0.55) | SPHK2SPHK1CES2CES1GPR84 | |
| SCHEMBL3180398 | 1.00 | SPHK2 (0.55) | SPHK2SPHK1CES2CES1GPR84 | |
| SCHEMBL7519178 | 1.00 | SPHK2 (0.55) | SPHK2SPHK1CES2CES1GPR84 | |
| SCHEMBL608443 | 1.00 | SPHK2 (0.55) | SPHK2SPHK1CES2CES1GPR84 | |
| SCHEMBL7516420 | 1.00 | SPHK2 (0.55) | SPHK2SPHK1CES2CES1GPR84 | |
| SCHEMBL28880442 | 1.00 | SPHK2 (0.55) | SPHK2SPHK1CES2CES1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778866-A | MONOMER OF FLUORINATED ALKYL ESTERS OF ACRYLIC AND METHACRYLIC ACIDS; DIELECTRIC FOR HIGH VOLTAGE CABLES; TREEING | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1988-10-18 | — | — | US | claimed |
| US-20240141110-A1 | POLYSILOXANE DISPERSING AGENT | BYK-CHEMIE GMBH (DE) | 2024-05-02 | — | — | US | disclosed |
| EP-4298153-A1 | POLYSILOXANE DISPERSING AGENT | BYK-Chemie GmbH (DE) | 2024-01-03 | — | — | EP | disclosed |
| CN-112566620-B | Oil-in-water type emulsified cosmetic | 株式会社资生堂 | 2023-05-02 | — | — | CN | disclosed |
| WO-2022179972-A1 | POLYSILOXANE DISPERSING AGENT | BYK-CHEMIE GMBH (DE) | 2022-09-01 | — | — | WO | disclosed |
| US-20210330558-A1 | OIL-IN-WATER EMULSION COSMETIC | SHISEIDO COMPANY, LTD. (JP) | 2021-10-28 | — | — | US | disclosed |
| EP-3831361-A1 | OIL-IN-WATER EMULSION COSMETIC | Shiseido Company, Ltd. (JP) | 2021-06-09 | — | — | EP | disclosed |
| EP-3269724-B1 | MONONUCLEAR IRON COMPLEX AND ORGANIC SYNTHESIS REACTION USING SAME | UNIV KYUSHU NAT UNIV CORP (JP) | 2020-04-22 | — | — | EP | disclosed |
| EP-3118205-B1 | MONONUCLEAR RUTHENIUM COMPLEX AND ORGANIC SYNTHESIS REACTION USING SAME | UNIV KYUSHU NAT UNIV CORP (JP) | 2020-04-22 | — | — | EP | disclosed |
| WO-2020027164-A1 | OIL-IN-WATER EMULSION COSMETIC | 株式会社 資生堂 | 2020-02-06 | — | — | WO | disclosed |
| US-20050053571-A1 | Cosmetic composition | DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) | 2005-03-10 | — | — | US | disclosed |
| US-20040253197-A1 | adding organic acids, phosphoric acid or phosphates to crosslinking organopolysiloxane polymer having a polyoxyalkylene group, heat treatment, neutralization; an emulsifying oil; excellent storage stability and does not emit an unpleasant odor; very little propionaldehyde produced | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2004-12-16 | — | — | US | disclosed |
| EP-1424365-A9 | PASTY COMPOSITION AND COSMETICS CONTAINING THE SAME | Shin-Etsu Chemical Co., Ltd. (JP) | 2004-12-15 | — | — | EP | disclosed |
| US-20040241126-A1 | Cosmetic | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2004-12-02 | — | — | US | disclosed |
| EP-1481660-A1 | Cosmetic | Shin-Etsu Chemical Co., Ltd. (JP) | 2004-12-01 | — | — | EP | disclosed |
| EP-1424365-A1 | PASTY COMPOSITION AND COSMETICS CONTAINING THE SAME | Shin-Etsu Chemical Co., Ltd. (JP) | 2004-06-02 | — | — | EP | disclosed |
| US-20030199660-A1 | Silicone polymer, silicone composition, and cosmetic preparation containing the same | SHIN-ETSU CHEMCIAL CO., LTD. (JP) | 2003-10-23 | — | — | US | disclosed |
| EP-1291376-A1 | SILICONE POLYMER, SILICONE COMPOSITION, AND COSMETIC PREPARATION CONTAINING THE SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-4778866-A | MONOMER OF FLUORINATED ALKYL ESTERS OF ACRYLIC AND METHACRYLIC ACIDS; DIELECTRIC FOR HIGH VOLTAGE CABLES; TREEING | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1988-10-18 | — | — | US | disclosed |
| EP-0209299-A1 | Copolymers of ethylene and unsaturated ester | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1987-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040253197-A1 | adding organic acids, phosphoric acid or phosphates to crosslinking organopolysiloxane polymer having a polyoxyalkylene group, heat treatment, neutralization; an emulsifying oil; excellent storage stability and does not emit an unpleasant odor; very little propionaldehyde produced | OR10J3, PLOD2, PHYKPL | SPHK2 2108/4885SPHK1 1568/4885CES2 1107/4885 |
| US-20050053571-A1 | Cosmetic composition | AHR, TRPA1, H1-0 | SPHK2 4274/4885SPHK1 4151/4885CES2 1131/4885 |
| US-20040241126-A1 | Cosmetic | SGMS1, ALG3, RIF1 | SPHK2 1641/4885SPHK1 739/4885CES2 434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.