SCHEMBL9427720

SCHEMBL9427720

CCO[Si](C)(CCC(=O)O)OCC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.40
HDAC3 O15379 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
AKR1B1 P15121 1/20 0.36
LMNA P02545 2/20 0.35
ALKBH5 Q6P6C2 1/20 0.35
SUCNR1 Q9BXA5 1/20 0.35
EGLN1 Q9GZT9 1/20 0.35
GPR84 Q9NQS5 7/20 0.34
PPARG P37231 7/20 0.34
PPARD Q03181 7/20 0.34
PPARA Q07869 7/20 0.34
HDAC11 Q96DB2 5/20 0.34
TSHR P16473 4/20 0.34
PTPN1 P18031 3/20 0.34
ALDH1A1 P00352 2/20 0.34
TLR2 O60603 2/20 0.34
TDP1 Q9NUW8 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2046598 0.87 AKR1B1 (0.43) AKR1B1LMNAGPR84PPARGPPARD
SCHEMBL192745 0.84 GPR84 (0.48) AKR1B1LMNAGPR84PPARGPPARD
SCHEMBL16592783 0.82 FFAR3 (0.40) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL3911434 0.80 ALOX15 (0.36) MEN1ALOX15KMT2A
SCHEMBL49439 0.79 FFAR3 (0.42) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL9705684 0.78 CYP1A2 (0.45) LMNATSHRALDH1A1HSD17B10
SCHEMBL11905619 0.78 PLA2G2A (0.36) AKR1B1TSHR
SCHEMBL19405693 0.78 KDM5A (0.44) TSHR
SCHEMBL4450916 0.77
SCHEMBL28143860 0.77 FFAR3 (0.40) FFAR3HDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101639628-B Radioactive linear composition for forming of coloring layer, color filter and color liquid crystal display element JSR CORP JP 2013-04-03 CN disclosed
CN-101646718-B Curable resin composition, protective film, and method for forming protective film JSR CORP JP 2013-04-03 CN disclosed
CN-101226329-B Radiation sensitive resin composition, laminated insulating film, micro lens and preparation method thereof JSR CORP 2012-09-05 CN disclosed
CN-101646718-A The formation method of curable resin composition, protective membrane and protective membrane JSR CORP JP 2010-02-10 CN disclosed
CN-101639628-A Radioactive linear composition for forming of coloring layer, color filter and color liquid crystal display element JSR CORP JP 2010-02-03 CN disclosed
CN-101226329-A Radiation sensitive resin composition, laminated insulating film, micro lens and preparation method thereof JSR CORP (JP) 2008-07-23 CN disclosed
US-5310439-A Process for bonding a molded article of a thermoplastic saturated norbornene resin NIPPON ZEON CO., LTD. (JP) 1994-05-10 US disclosed
EP-0370464-A2 Curable resin composition Kanegafuchi Chemical Industry Co., Ltd. (JP) 1990-05-30 EP disclosed