Oxybenzone

Oxybenzone

SCHEMBL942845

COc1ccc(C(=O)c2ccccc2)c(O)c1.[NaH]

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 6/20 0.97
LMNA P02545 6/20 0.97
ALDH1A1 P00352 5/20 0.97
MAPK1 P28482 3/20 0.97
HTT P42858 3/20 0.97
CYP1A2 P05177 2/20 0.97
PGR P06401 2/20 0.97
SLC6A2 P23975 2/20 0.97
CYP2C19 P33261 2/20 0.97
CYP2D6 P10635 1/20 0.97
PDE4A P27815 1/20 0.97
HRH1 P35367 1/20 0.97
SLC6A3 Q01959 1/20 0.97
PDE4D Q08499 1/20 0.97
RAB9A P51151 5/20 0.72
NPC1 O15118 5/20 0.72
CYP3A4 P08684 3/20 0.71
ALOX15 P16050 2/20 0.71
ADORA3 P0DMS8 1/20 0.71
AR P10275 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxybenzone SCHEMBL5161586 0.98 HPGD (1.00) HPGDLMNAALDH1A1MAPK1HTT
Oxybenzone SCHEMBL15551 0.98 HPGD (1.00) HPGDLMNAALDH1A1MAPK1HTT
Oxybenzone SCHEMBL29355332 0.98 HPGD (1.00) HPGDLMNAALDH1A1MAPK1HTT
Oxybenzone SCHEMBL6674080 0.98 HPGD (1.00) HPGDLMNAALDH1A1MAPK1HTT
Oxybenzone SCHEMBL419361 0.98 HPGD (1.00) HPGDLMNAALDH1A1MAPK1HTT
Oxybenzone SCHEMBL11414020 0.97 HPGD (0.97) HPGDLMNAALDH1A1MAPK1HTT
Oxybenzone SCHEMBL31403363 0.97 HPGD (0.97) HPGDLMNAALDH1A1MAPK1HTT
Oxybenzone SCHEMBL550167 0.97 HPGD (0.97) HPGDLMNAALDH1A1MAPK1HTT
Oxybenzone SCHEMBL7243732 0.97 HPGD (0.97) HPGDLMNAALDH1A1MAPK1HTT
Oxybenzone SCHEMBL7191990 0.97 HPGD (0.97) HPGDLMNAALDH1A1MAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023286725-A1 UV ABSORBER AND MANUFACTURING METHOD THEREOF, COMPOSITION, MOLDED BODY AND COATING FILM 東洋インキSCホールディングス株式会社 2023-01-19 WO disclosed
US-20150335692-A1 ORAL PREPARATION, INJECTION PREPARATION, EXTERNAL SKIN PREPARATION AND COSMETIC METHOD FOR PREVENTING OR IMPROVING WRINKLES SHISEIDO COMPANY, LTD. (JP) 2015-11-26 US disclosed
US-20110020477-A1 ORAL PREPARATION, INJECTION PREPARATION, EXTERNAL SKIN PREPARATION AND COSMETIC METHOD FOR PREVENTING OR IMPROVING WRINKLES SHISEIDO COMPANY, LTD. 2011-01-27 US disclosed
US-20100008879-A1 Whitening agent SHISEIDO COMPANY, LTD. 2010-01-14 US disclosed
US-20080003189-A1 Whitening Agent SHISEIDO COMPANY. LTD. (JP) 2008-01-03 US disclosed
US-20060057229-A1 External skin preparations for suppressing sebum secretion SHISEIDO COMPANY, LTD. (JP) 2006-03-16 US disclosed
EP-1284134-A2 EXTERNAL SKIN PREPARATIONS FOR SUPPRESSING SEBUM SECRETION SHISEIDO COMPANY LIMITED (JP) 2003-02-19 EP disclosed
US-6419962-B1 PLANT EXTRACT IN CARRIER SHISEIDO COMPANY, LTD. (JP) 2002-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060057229-A1 External skin preparations for suppressing sebum secretion MMP7, MMP8, MMP2 HPGD 242/4885LMNA 3581/4885ALDH1A1 3438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.