SCHEMBL9428522

SCHEMBL9428522

CON1C(C)(C)CC(CCCCNc2nc(NCCCCC3CC(C)(C)N(OC)C(C)(C)C3)nc(NCC(=O)O)n2)CC1(C)C

nearest known ligand 0.30

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KCNH3 Q9ULD8 1/20 0.30
CA12 O43570 2/20 0.30
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30
CA4 P22748 2/20 0.30
CA6 P23280 2/20 0.30
CA5A P35218 2/20 0.30
CA7 P43166 2/20 0.30
CA9 Q16790 2/20 0.30
CA14 Q9ULX7 2/20 0.30
CA3 P07451 1/20 0.30
CA13 Q8N1Q1 1/20 0.30
CA5B Q9Y2D0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9428572 0.91 KDM4E (0.39) CA12CA1CA2CA9CA14
SCHEMBL9429306 0.90 HTR2C (0.33) CA1CA2
SCHEMBL9427947 0.86 KDM4E (0.32)
SCHEMBL9427851 0.86 KMT2A (0.40) KCNH3
SCHEMBL9428321 0.85 KMT2A (0.36) KCNH3
SCHEMBL9429263 0.85 NAAA (0.33)
SCHEMBL9429384 0.85 KMT2A (0.42) KCNH3
SCHEMBL9422664 0.83 HTR7 (0.37)
SCHEMBL7458930 0.83 KMT2A (0.40) CA12CA1CA2CA9CA14
SCHEMBL9428396 0.82 KMT2A (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5300544-A Non-migrating 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperdine 1,3,5-triazine derivatives as polymer stabilizers CIBA-GEIGY CORPORATION (US) 1994-04-05 US disclosed
US-5216156-A Stabilizers having functional groups which chemically bond with polymer substrates CIBA-GEIGY CORPORATION (US) 1993-06-01 US disclosed