Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 6/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9428248 | 0.99 | MEN1 (0.47) | MEN1MAPTKMT2AHRH1HRH3 | |
| SCHEMBL9428457 | 0.87 | LTA4H (0.55) | MEN1KMT2AHRH1HRH3HTR1A | |
| Hydrochloric Acid SCHEMBL9428931 | 0.86 | LTA4H (0.54) | MEN1KMT2AHRH1HRH3HTR1A | |
| SCHEMBL9428511 | 0.86 | DRD2 (0.44) | MEN1KMT2AHRH1HRH3AR | |
| SCHEMBL9428603 | 0.86 | MCOLN2 (0.44) | MEN1MAPTKMT2AHRH1TRIM24 | |
| Hydrochloric Acid SCHEMBL9428714 | 0.85 | DRD2 (0.43) | MEN1MAPTKMT2AHRH1HRH3 | |
| SCHEMBL9879101 | 0.85 | HRH3 (0.47) | MEN1KMT2AHRH1HRH3 | |
| Hydrochloric Acid SCHEMBL9428258 | 0.85 | MAPT (0.45) | MEN1MAPTKMT2AHRH1TRIM24 | |
| SCHEMBL9429006 | 0.84 | HRH1 (0.60) | MEN1KMT2AHRH1HRH3HRH2 | |
| Hydrochloric Acid SCHEMBL9428526 | 0.84 | HRH3 (0.46) | MEN1KMT2AHRH1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |