Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 8/20 | 0.60 |
| ▸ | DRD3 | P35462 | 4/20 | 0.60 |
| ▸ | HTR1A | P08908 | 3/20 | 0.60 |
| ▸ | DRD2 | P14416 | 3/20 | 0.60 |
| ▸ | HTR2A | P28223 | 3/20 | 0.60 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HRH2 | P25021 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9429366 | 0.94 | ALDH1A1 (0.52) | HRH1DRD3HTR1ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL9428580 | 0.92 | MEN1 (0.51) | HRH1DRD3HTR1ADRD2HTR2A | |
| SCHEMBL9428835 | 0.89 | DRD2 (0.54) | HRH1DRD3HTR1ADRD2HTR2A | |
| SCHEMBL9428736 | 0.88 | DRD3 (0.53) | HRH1DRD3HTR1ADRD2HTR2A | |
| SCHEMBL9428476 | 0.88 | ALDH1A1 (0.58) | HRH1DRD3HTR1ADRD2HTR2A | |
| SCHEMBL9428373 | 0.88 | DRD2 (0.58) | HRH1DRD3HTR1ADRD2HTR2A | |
| SCHEMBL9429324 | 0.88 | DRD2 (0.56) | HRH1DRD3HTR1ADRD2HTR2A | |
| SCHEMBL9428466 | 0.88 | MEN1 (0.49) | HRH1DRD3HTR1ADRD2HTR2A | |
| SCHEMBL9428590 | 0.87 | DRD2 (0.48) | HRH1DRD3HTR1ADRD2HTR2A | |
| SCHEMBL9428306 | 0.87 | LMNA (0.59) | DRD3HTR1ADRD2HTR2ATMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |