Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9589972 | 0.89 | ALOX5 (0.56) | PTGS2ALDH1A1PPARARAB9AMAPT | |
| SCHEMBL9590715 | 0.89 | ALOX5 (0.56) | PTGS2ALDH1A1PPARARAB9AMAPT | |
| SCHEMBL9427934 | 0.89 | PPARA (0.47) | ALDH1A1PPARARAB9AMAPTKDM4E | |
| SCHEMBL9427325 | 0.87 | ALDH1A1 (0.48) | ALDH1A1PPARARAB9AMAPTKDM4E | |
| SCHEMBL9427556 | 0.86 | RAB9A (0.49) | ALDH1A1PPARARAB9AMAPTKDM4E | |
| SCHEMBL13140274 | 0.84 | FFAR1 (0.53) | ALDH1A1PPARARAB9AMAPTKDM4E | |
| SCHEMBL9427979 | 0.84 | ALOX5 (0.50) | ALDH1A1PPARARAB9AALOX5NPC1 | |
| SCHEMBL9428016 | 0.83 | ALOX5 (0.63) | ALDH1A1PPARARAB9AMAPTKDM4E | |
| SCHEMBL9428441 | 0.81 | KDM4E (0.58) | ALDH1A1PPARARAB9AMAPTKDM4E | |
| SCHEMBL9427717 | 0.81 | ALOX5 (0.52) | ALDH1A1PPARARAB9AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364944-A | Antiinflammatory, antiallergic and cytoprotective agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-11-15 | — | — | US | disclosed |
| US-5218124-A | Antiinflammatory agents, antiallergens and cytoprotective agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-06-08 | — | — | US | disclosed |