Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9428016 | 0.91 | ALOX5 (0.63) | ALOX5PPARAALDH1A1NPC1RAB9A | |
| SCHEMBL9472825 | 0.86 | PPARA (0.46) | ALOX5PPARAALDH1A1NPC1RAB9A | |
| SCHEMBL9428612 | 0.84 | PTGS2 (0.51) | ALOX5PPARAALDH1A1NPC1RAB9A | |
| SCHEMBL9427934 | 0.84 | PPARA (0.47) | ALOX5PPARAALDH1A1NPC1RAB9A | |
| SCHEMBL9427325 | 0.83 | ALDH1A1 (0.48) | ALOX5PPARAALDH1A1NPC1RAB9A | |
| SCHEMBL9427717 | 0.83 | ALOX5 (0.52) | ALOX5PPARAALDH1A1NPC1RAB9A | |
| SCHEMBL9428747 | 0.80 | ALOX5 (0.60) | ALOX5PPARAALDH1A1NPC1RAB9A | |
| SCHEMBL13140274 | 0.80 | FFAR1 (0.53) | ALOX5PPARAALDH1A1NPC1RAB9A | |
| SCHEMBL9427556 | 0.79 | RAB9A (0.49) | ALOX5PPARAALDH1A1NPC1RAB9A | |
| SCHEMBL19509921 | 0.78 | ALDH1A1 (0.60) | PPARAALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5218124-A | Antiinflammatory agents, antiallergens and cytoprotective agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-06-08 | — | — | US | claimed |
| US-5364944-A | Antiinflammatory, antiallergic and cytoprotective agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-11-15 | — | — | US | disclosed |
| US-5218124-A | Antiinflammatory agents, antiallergens and cytoprotective agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-06-08 | — | — | US | disclosed |