Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 3/20 | 0.51 |
| ▸ | HRH2 | P25021 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.48 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9428669 | 0.94 | HRH3 (0.64) | KDM4EHRH3HRH1HRH2DRD2 | |
| SCHEMBL9429182 | 0.93 | HRH3 (0.64) | KDM4EHRH3HRH1HRH2 | |
| SCHEMBL9429612 | 0.84 | MEN1 (0.55) | KDM4EALDH1A1RAB9ADRD3DRD2 | |
| SCHEMBL9429366 | 0.84 | ALDH1A1 (0.52) | KDM4EALDH1A1HRH1DRD3DRD2 | |
| Hydrochloric Acid SCHEMBL9428814 | 0.83 | SIGMAR1 (0.54) | KDM4EALDH1A1RAB9ADRD3DRD2 | |
| Hydrochloric Acid SCHEMBL9428580 | 0.83 | MEN1 (0.51) | ALDH1A1HRH1DRD3DRD2 | |
| SCHEMBL9429765 | 0.82 | HRH3 (0.52) | HRH3HRH1DRD2 | |
| SCHEMBL9428656 | 0.82 | ALDH1A1 (0.50) | ALDH1A1HRH3HRH1 | |
| SCHEMBL9429465 | 0.81 | MAPT (0.52) | KDM4EALDH1A1RAB9AHRH1DRD3 | |
| SCHEMBL9428719 | 0.81 | HRH3 (0.47) | KDM4EALDH1A1HRH3HRH1HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |