Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 5/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 2/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9428580 | 0.99 | MEN1 (0.51) | ALDH1A1MEN1KMT2AHRH1DRD2 | |
| SCHEMBL9429006 | 0.94 | HRH1 (0.60) | ALDH1A1MEN1KMT2AHRH1DRD2 | |
| SCHEMBL9429612 | 0.87 | MEN1 (0.55) | ALDH1A1MEN1KMT2ADRD2HTR1A | |
| Hydrochloric Acid SCHEMBL9428814 | 0.86 | SIGMAR1 (0.54) | ALDH1A1MEN1KMT2ADRD2HTR1A | |
| SCHEMBL9428162 | 0.84 | LTA4H (0.47) | ALDH1A1MEN1KMT2AHRH1DRD2 | |
| SCHEMBL9428772 | 0.84 | KDM4E (0.56) | ALDH1A1HRH1DRD2DRD3KDM4E | |
| SCHEMBL9386459 | 0.83 | LTA4H (0.58) | ALDH1A1MEN1KMT2AHRH1DRD3 | |
| SCHEMBL9428736 | 0.82 | DRD3 (0.53) | ALDH1A1HRH1DRD2HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL9384427 | 0.82 | LTA4H (0.57) | ALDH1A1MEN1KMT2AHRH1DRD3 | |
| SCHEMBL9428835 | 0.82 | DRD2 (0.54) | ALDH1A1MEN1KMT2AHRH1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |