Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9428383 | 0.95 | MAPT (0.59) | MAPTHTR1ADRD3DRD2LMNA | |
| SCHEMBL9428178 | 0.94 | MAPT (0.55) | MAPTHTR1AKDM4EDRD2ALDH1A1 | |
| SCHEMBL9429031 | 0.86 | HTR1A (0.55) | MAPTHTR1ADRD3DRD2LMNA | |
| Hydrochloric Acid SCHEMBL9429549 | 0.85 | HTR1A (0.54) | MAPTHTR1ADRD3DRD2LMNA | |
| SCHEMBL9429424 | 0.85 | DRD2 (0.53) | HTR1AKDM4EDRD3DRD2DRD1 | |
| SCHEMBL9429014 | 0.84 | MEN1 (0.53) | MAPTHTR1ADRD3DRD2ALDH1A1 | |
| SCHEMBL9428459 | 0.84 | KCNA5 (0.41) | HTR1ADRD3ALDH1A1MEN1KMT2A | |
| SCHEMBL9428162 | 0.83 | LTA4H (0.47) | MAPTHTR1ADRD3DRD2ALDH1A1 | |
| SCHEMBL9384119 | 0.83 | HTR1A (0.45) | MAPTHTR1AKDM4EALDH1A1LMNA | |
| SCHEMBL9429060 | 0.83 | HTR1A (0.49) | MAPTHTR1AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |