Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 9/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9429742 | 0.86 | MAPT (0.55) | MAPTHTR1AL3MBTL1DRD2MAOB | |
| SCHEMBL9428383 | 0.79 | MAPT (0.59) | MAPTHTR1ADRD2DRD3MAOB | |
| SCHEMBL9429316 | 0.77 | ALDH1A1 (0.46) | MAPTHTR1AMAOBHTR2A | |
| SCHEMBL9428178 | 0.77 | MAPT (0.55) | MAPTHTR1AL3MBTL1DRD2MAOB | |
| SCHEMBL9383519 | 0.75 | HTR1A (0.49) | MAPTHTR1AHTR2A | |
| SCHEMBL9429465 | 0.74 | MAPT (0.52) | MAPTHTR1ADRD2DRD3MAOB | |
| SCHEMBL24395441 | 0.74 | MAPT (0.72) | MAPTHTR1AL3MBTL1MAOBABCB1 | |
| Oxalic Acid SCHEMBL9428165 | 0.72 | KDM4E (0.57) | MAPTHTR1ADRD2DRD4DRD3 | |
| SCHEMBL9429031 | 0.71 | HTR1A (0.55) | MAPTHTR1ADRD2DRD3 | |
| SCHEMBL9429342 | 0.71 | DRD3 (0.56) | HTR1ADRD2DRD4DRD3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |