Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 8/20 | 0.46 |
| ▸ | HTR2A | P28223 | 8/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9383519 | 0.85 | HTR1A (0.49) | ALDH1A1HTR1AHTR2AKDM4ENPC1 | |
| SCHEMBL9429637 | 0.83 | HTR1A (0.48) | ALDH1A1THRBHTR1AHTR2ASMN1; SMN2 | |
| SCHEMBL9428894 | 0.81 | DRD2 (0.53) | HTR1AHTR2A | |
| Oxalic Acid SCHEMBL9429238 | 0.81 | MEN1 (0.55) | ALDH1A1HTR1AHTR2AMEN1KMT2A | |
| SCHEMBL9428872 | 0.77 | MAPT (0.53) | HTR1AHTR2AMAPTMAOB | |
| Oxalic Acid SCHEMBL9428165 | 0.76 | KDM4E (0.57) | ALDH1A1HTR1AHTR2AKDM4ENPC1 | |
| SCHEMBL9429342 | 0.75 | DRD3 (0.56) | ALDH1A1HTR1AHTR2AKDM4ENPC1 | |
| SCHEMBL9428383 | 0.73 | MAPT (0.59) | HTR1AMAPTMAOBLMNAHTR2B | |
| SCHEMBL9388964 | 0.72 | HTR1A (0.50) | ALDH1A1HTR1AHTR2AKDM4ESMN1; SMN2 | |
| SCHEMBL9428210 | 0.71 | ADRA1B (0.47) | ALDH1A1THRBHTR1AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |