Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 8/20 | 0.52 |
| ▸ | HRH1 | P35367 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9428383 | 0.90 | MAPT (0.59) | HTR1AHRH1MAPTADRA1ADRD2 | |
| SCHEMBL9429031 | 0.90 | HTR1A (0.55) | HTR1AHRH1MAPTADRA1ADRD2 | |
| Hydrochloric Acid SCHEMBL9429549 | 0.89 | HTR1A (0.54) | HTR1AHRH1MAPTADRA1ADRD2 | |
| SCHEMBL9429658 | 0.88 | HTR1A (0.52) | HTR1AHRH1MAPTADRA1ADRD2 | |
| SCHEMBL9428178 | 0.87 | MAPT (0.55) | HTR1AHRH1MAPTDRD2LMNA | |
| SCHEMBL9429060 | 0.86 | HTR1A (0.49) | HTR1AHRH1MAPTADRA1AADRA1D | |
| SCHEMBL9428613 | 0.85 | HTR1A (0.49) | MEN1KMT2AHTR1AHRH1MAPT | |
| SCHEMBL9429697 | 0.85 | DRD2 (0.57) | HTR1AHRH1MAPTADRA1ADRD2 | |
| SCHEMBL9428911 | 0.85 | HRH1 (0.41) | HTR1AHRH1MAPTADRA1ADRD2 | |
| SCHEMBL9429465 | 0.84 | MAPT (0.52) | MEN1KMT2AGAAHTR1AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |