Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.52 |
| ▸ | HRH1 | P35367 | 9/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9429014 | 0.88 | MEN1 (0.53) | HTR1AHRH1ADRA1DADRA1AADRA1B | |
| SCHEMBL9429031 | 0.87 | HTR1A (0.55) | HTR1AHRH1ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL9429549 | 0.86 | HTR1A (0.54) | HTR1AHRH1ADRA1DADRA1AADRA1B | |
| SCHEMBL9428383 | 0.85 | MAPT (0.59) | HTR1AHRH1ADRA1DADRA1AADRA1B | |
| SCHEMBL9428178 | 0.82 | MAPT (0.55) | HTR1AHRH1MAPTDRD2 | |
| SCHEMBL9429060 | 0.82 | HTR1A (0.49) | HTR1AHRH1ADRA1DADRA1AADRA1B | |
| SCHEMBL9428613 | 0.81 | HTR1A (0.49) | HTR1AHRH1ADRA1DADRA1AADRA1B | |
| SCHEMBL9428634 | 0.81 | KEAP1 (0.50) | HTR1AHRH1ADRA1DADRA1AADRA1B | |
| SCHEMBL9428628 | 0.81 | KEAP1 (0.50) | HTR1AHRH1ADRA1DADRA1AADRA1B | |
| SCHEMBL9429465 | 0.80 | MAPT (0.52) | HTR1AHRH1MAPTDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |