Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CCR3 | P51677 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL943648 | 0.73 | CHRM1 (0.36) | SIGMAR1MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL942650 | 0.73 | SIGMAR1 (0.52) | SIGMAR1POLBALDH1A1TSHR | |
| SCHEMBL1553960 | 0.71 | SIGMAR1 (0.47) | SIGMAR1MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL29957200 | 0.70 | CHRM2 (0.44) | SIGMAR1CHRM2CHRM1POLBHSD17B10 | |
| SCHEMBL27549748 | 0.68 | METAP1 (0.50) | SIGMAR1METAP1 | |
| SCHEMBL21540294 | 0.68 | METAP1 (0.55) | METAP1 | |
| SCHEMBL10305559 | 0.68 | METAP1 (0.55) | METAP1 | |
| SCHEMBL1017572 | 0.67 | SIGMAR1 (0.39) | SIGMAR1CHRM2CHRM1POLBHSD17B10 | |
| SCHEMBL931400 | 0.66 | METAP1 (0.49) | SIGMAR1METAP1 | |
| SCHEMBL13582 | 0.66 | METAP1 (0.49) | SIGMAR1METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011000945-A2 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-01-06 | — | — | WO | disclosed |