Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 5/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | GHSR | Q92847 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL942902 | 0.73 | SIGMAR1 (0.48) | CHRM1SIGMAR1CHRM5CHRM2CHRM4 | |
| SCHEMBL1554587 | 0.68 | EPHX2 (0.41) | SIGMAR1DPP4ALDH1A1 | |
| SCHEMBL1017572 | 0.66 | SIGMAR1 (0.39) | CHRM1SIGMAR1CHRM2HRH3POLB | |
| SCHEMBL3632697 | 0.66 | GHSR (0.46) | CHRM1CHRM2MEN1KMT2AALDH1A1 | |
| SCHEMBL16515908 | 0.65 | L3MBTL3 (0.42) | CHRM1SIGMAR1CHRM5CHRM2CHRM4 | |
| SCHEMBL3653777 | 0.65 | SIGMAR1 (0.40) | SIGMAR1CHRM5CHRM3 | |
| SCHEMBL12250827 | 0.65 | MEN1 (0.40) | CHRM1SIGMAR1CHRM5CHRM2CHRM4 | |
| SCHEMBL1083799 | 0.65 | MEN1 (0.40) | CHRM1SIGMAR1CHRM5CHRM2CHRM4 | |
| SCHEMBL12250826 | 0.65 | MEN1 (0.40) | CHRM1SIGMAR1CHRM5CHRM2CHRM4 | |
| SCHEMBL18500430 | 0.64 | MEN1 (0.41) | CHRM1SIGMAR1CHRM5CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011000945-A9 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-04-07 | — | — | WO | disclosed |
| WO-2011000945-A2 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-01-06 | — | — | WO | disclosed |