Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14655522 | 0.84 | EPHX1 (0.52) | EPHX1KCNH2 | |
| SCHEMBL944062 | 0.81 | EPHX1 (0.46) | EPHX1HRH3KCNH2KDM4E | |
| SCHEMBL6187047 | 0.78 | EPHX1 (0.46) | SIGMAR1EPHX1KCNH2 | |
| SCHEMBL29957200 | 0.75 | CHRM2 (0.44) | SIGMAR1POLBHSD17B10CHRM2CHRM1 | |
| SCHEMBL1554795 | 0.75 | EPHX2 (0.49) | SIGMAR1POLBEPHX1KDM4EALDH1A1 | |
| SCHEMBL1555148 | 0.74 | EPHX1 (0.39) | POLBEPHX1KDM4E | |
| SCHEMBL1017572 | 0.72 | SIGMAR1 (0.39) | SIGMAR1POLBHSD17B10CHRM2CHRM1 | |
| SCHEMBL942902 | 0.71 | SIGMAR1 (0.48) | SIGMAR1POLBHSD17B10CHRM2CHRM1 | |
| SCHEMBL1555261 | 0.69 | SIGMAR1 (0.35) | SIGMAR1EPHX1KMT2AKDM4E | |
| SCHEMBL3216528 | 0.69 | POLB (0.55) | POLBHSD17B10MEN1KMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011000945-A9 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-04-07 | — | — | WO | disclosed |