Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9428036 | 0.80 | CYP1A2 (0.44) | PTGS2HSD17B10 | |
| SCHEMBL9641605 | 0.78 | PTGS2 (0.36) | PTGS2HSD17B10 | |
| SCHEMBL9428059 | 0.75 | APOBEC3G (0.50) | APOBEC3GPTGS2 | |
| SCHEMBL10367304 | 0.75 | APOBEC3G (0.53) | APOBEC3GPTGS2 | |
| SCHEMBL7385335 | 0.74 | APOBEC3G (0.52) | APOBEC3GPTGS2 | |
| SCHEMBL11290456 | 0.69 | PTPN1 (0.35) | — | |
| SCHEMBL9429054 | 0.69 | PTGS2 (0.36) | APOBEC3GPTGS2 | |
| SCHEMBL9727526 | 0.69 | APOBEC3G (0.53) | APOBEC3GPTGS2 | |
| SCHEMBL9640916 | 0.68 | GSK3B (0.33) | HSD17B10 | |
| SCHEMBL174237 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5314918-A | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1994-05-24 | — | — | US | disclosed |
| EP-0532674-A4 | LEUKOTRIENE ANTAGONISTS | — | 1993-04-07 | — | — | EP | disclosed |
| EP-0532674-A1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-03-24 | — | — | EP | disclosed |
| US-5143931-A | 2-Phenyl-2((tetrazolyl or imidazolyl)thio)alkanoic acid derivatives; antiphylactic and bronchodilator agents | SMITHKLINE BEECHAM CORPORATION (US) | 1992-09-01 | — | — | US | disclosed |
| EP-0296731-B1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-08-26 | — | — | EP | disclosed |
| US-5135938-A | Bronchodilator | SMITHKLINE BEECHAM CORPORATION (US) | 1992-08-04 | — | — | US | disclosed |
| WO-1991018889-A1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-12-12 | — | — | WO | disclosed |
| EP-0296732-B1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-09 | — | — | EP | disclosed |
| EP-0403249-A1 | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |
| EP-0296731-A1 | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1988-12-28 | — | — | EP | disclosed |
| EP-0296732-A1 | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1988-12-28 | — | — | EP | disclosed |