Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7385335 | 0.95 | APOBEC3G (0.52) | APOBEC3GNPC1LMNAPKMHTT | |
| SCHEMBL10365374 | 0.89 | APOBEC3G (0.57) | APOBEC3GPTGS2SLC6A4CYP1A2CYP2D6 | |
| SCHEMBL9428059 | 0.82 | APOBEC3G (0.50) | APOBEC3GPTGS2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9727526 | 0.81 | APOBEC3G (0.53) | APOBEC3GNPC1LMNAHTTRAB9A | |
| SCHEMBL26942237 | 0.77 | APOBEC3G (0.57) | APOBEC3GPTGS2SLC6A4 | |
| SCHEMBL9429059 | 0.75 | APOBEC3G (0.39) | APOBEC3GPTGS2 | |
| SCHEMBL2655184 | 0.75 | DHFR (0.41) | NPC1LMNAPKMHTTRAB9A | |
| SCHEMBL9379911 | 0.75 | MEN1 (0.55) | APOBEC3GNPC1LMNAPKMHTT | |
| SCHEMBL9645274 | 0.74 | SIRT1 (0.49) | NPC1LMNAPKMHTTRAB9A | |
| SCHEMBL5663275 | 0.73 | HTR7 (0.55) | NPC1LMNAPKMHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0206662-B1 | THIAZOLIDINE DERIVATIVES AND PROCESS FOR PREPARING THE SAME | Tanabe Seiyaku Co., Ltd. (JP) | 1990-05-09 | — | — | EP | disclosed |
| US-4777178-A | CARDIOTONIC AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1988-10-11 | — | — | US | disclosed |
| US-4689327-A | N-substituted-2-[2-[2-(4-phenylpiperazine-1-yl)ethoxy]phenyl]-thiazolidine-3-carboxamides useful as cardiotonic agent | TANABE SEIYAKU CO., LTD. (JP) | 1987-08-25 | — | — | US | disclosed |
| EP-0206662-A1 | Thiazolidine derivatives and process for preparing the same | Tanabe Seiyaku Co., Ltd. (JP) | 1986-12-30 | — | — | EP | disclosed |
| EP-0167355-A2 | Thiazolidine derivative and processes for preparing the same | Tanabe Seiyaku Co., Ltd. (JP) | 1986-01-08 | — | — | EP | disclosed |