Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 9/20 | 0.47 |
| ▸ | HTR1A | P08908 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9429424 | 0.95 | DRD2 (0.53) | DRD2DRD3DRD1HRH1HTR1A | |
| SCHEMBL9429060 | 0.86 | HTR1A (0.49) | HRH1HTR1AMAPTADRA1DADRA1A | |
| SCHEMBL9388310 | 0.85 | ALDH1A1 (0.51) | HRH1HTR1AMAPT | |
| SCHEMBL9428383 | 0.85 | MAPT (0.59) | DRD2DRD3HRH1HTR1AMAPT | |
| SCHEMBL9429031 | 0.85 | HTR1A (0.55) | DRD2DRD3HRH1HTR1AMAPT | |
| SCHEMBL9428613 | 0.85 | HTR1A (0.49) | DRD2HRH1HTR1AMAPTADRA1D | |
| Hydrochloric Acid SCHEMBL9429549 | 0.84 | HTR1A (0.54) | DRD2DRD3HRH1HTR1AMAPT | |
| SCHEMBL9429014 | 0.84 | MEN1 (0.53) | DRD2DRD3HRH1HTR1AMAPT | |
| SCHEMBL9428178 | 0.82 | MAPT (0.55) | DRD2HRH1HTR1AMAPT | |
| SCHEMBL9428270 | 0.82 | HTR1A (0.46) | DRD2DRD3HRH1HTR1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |