Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9428929 | 1.00 | SIGMAR1 (0.46) | SIGMAR1ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL9455455 | 0.81 | ADRA2A (0.35) | SIGMAR1ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL348623 | 0.79 | TSHR (0.52) | SIGMAR1ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL4918208 | 0.76 | IDO1 (0.42) | SMN1; SMN2LMNAALDH1A1POLBTDP1 | |
| SCHEMBL9429158 | 0.75 | SLC6A4 (0.41) | ALDH1A1SLC6A2 | |
| SCHEMBL1829180 | 0.73 | CALM1 (0.52) | POLB | |
| SCHEMBL6586984 | 0.73 | CALM1 (0.52) | POLB | |
| SCHEMBL2051544 | 0.73 | CALM1 (0.52) | POLB | |
| SCHEMBL270340 | 0.72 | ALDH1A1 (0.62) | ADRA2AADRA2BADRA2CADRA1DHTR1D | |
| SCHEMBL3452699 | 0.71 | CALM1 (0.57) | ADRA2AADRA2BADRA2CADRA1DHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5302620-A | Bisguanidines and fungicides containing them | BASF AKTIENGESELLSCHAFT (DE) | 1994-04-12 | — | — | US | disclosed |
| US-5242948-A | BISGUANIDINES AND FUNGICIDES CONTAINING THEM | BASF AKTIENGESELLSCHAFT (DE) | 1993-09-07 | — | — | US | disclosed |