Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.56 |
| ▸ | HTR1A | P08908 | 3/20 | 0.56 |
| ▸ | HTR2A | P28223 | 3/20 | 0.56 |
| ▸ | DRD3 | P35462 | 3/20 | 0.56 |
| ▸ | DRD1 | P21728 | 1/20 | 0.56 |
| ▸ | DRD5 | P21918 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.55 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.53 |
| ▸ | HRH1 | P35367 | 4/20 | 0.53 |
| ▸ | HRH2 | P25021 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9428228 | 0.99 | SIGMAR1 (0.55) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL9429336 | 0.96 | HRH3 (0.55) | DRD2HTR1AHTR2ADRD3DRD1 | |
| Hydrochloric Acid SCHEMBL9429865 | 0.95 | HRH3 (0.54) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL9429612 | 0.94 | MEN1 (0.55) | DRD2HTR1AHTR2ADRD3DRD1 | |
| Hydrochloric Acid SCHEMBL9428814 | 0.93 | SIGMAR1 (0.54) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL9428835 | 0.89 | DRD2 (0.54) | DRD2HTR1AHTR2ADRD3SIGMAR1 | |
| SCHEMBL9428720 | 0.89 | MEN1 (0.50) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL9428864 | 0.88 | KDM4E (0.57) | DRD2HTR1AHTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL9428327 | 0.88 | MEN1 (0.49) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL9428373 | 0.88 | DRD2 (0.58) | DRD2HTR1AHTR2ADRD3DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| US-5281625-A | Benzyl substituted guanidine derivatives, salts, and metal complexes | BASF AKTIENGESELLSCHAFT (DE) | 1994-01-25 | — | — | US | disclosed |
| US-5126374-A | For plants, seeds, soils, effective at low concentrations | BASF AKTIENGESELLSCHAFT (DE) | 1992-06-30 | — | — | US | disclosed |