Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTR5A | P47898 | 1/20 | 0.47 |
| ▸ | ATF4 | P18848 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9428741 | 0.99 | KDM4E (0.56) | KDM4EALDH1A1SMN1; SMN2DRD2HTR1A | |
| SCHEMBL9428694 | 0.90 | ATF4 (0.48) | KDM4EALDH1A1SMN1; SMN2DRD2HTR1A | |
| SCHEMBL9429324 | 0.88 | DRD2 (0.56) | DRD2HTR1AHTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL9428228 | 0.87 | SIGMAR1 (0.55) | DRD2HTR1AHTR2AHRH1 | |
| SCHEMBL9428306 | 0.85 | LMNA (0.59) | SMN1; SMN2DRD2HTR1AHTR2AMEN1 | |
| SCHEMBL9429336 | 0.85 | HRH3 (0.55) | DRD2HTR1AHTR2AMEN1KMT2A | |
| SCHEMBL9428835 | 0.84 | DRD2 (0.54) | ALDH1A1DRD2HTR1AHTR2AHTR7 | |
| SCHEMBL9428720 | 0.84 | MEN1 (0.50) | ALDH1A1SMN1; SMN2DRD2HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL9428802 | 0.84 | KMT2A (0.58) | SMN1; SMN2DRD2HTR2AHTR7ADRA1A | |
| Hydrochloric Acid SCHEMBL9429865 | 0.84 | HRH3 (0.54) | DRD2HTR1AHTR2AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |