Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 12/20 | 0.47 |
| ▸ | HTR3B | O95264 | 12/20 | 0.47 |
| ▸ | HTR3A | P46098 | 12/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 12/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 12/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444191 | 0.75 | HTR3E (0.45) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL30713425 | 0.70 | DHODH (0.46) | — | |
| SCHEMBL15491449 | 0.70 | HSD17B10 (0.48) | — | |
| SCHEMBL6924495 | 0.69 | ACHE (0.49) | — | |
| SCHEMBL8124347 | 0.68 | GRM2 (0.48) | — | |
| SCHEMBL3226084 | 0.68 | DHODH (0.44) | — | |
| SCHEMBL6647772 | 0.68 | PARP1 (0.67) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL6669896 | 0.67 | DHODH (0.41) | — | |
| SCHEMBL6672250 | 0.67 | HTR3E (0.50) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL15491436 | 0.67 | DHODH (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5319085-A | Antiemetic agents; anticarcinogenic agent-induced vomiting; antianxiolytic agents; psychological disorders | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-06-07 | — | — | US | claimed |
| EP-0564650-A1 | QUINOLINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-10-13 | — | — | EP | claimed |