Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16433675 | 0.75 | USP30 (0.31) | — | |
| SCHEMBL9369273 | 0.75 | NLRP3 (0.37) | HTTNPSR1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL8573718 | 0.72 | ALDH1A1 (0.38) | HTTPOLBSMN1; SMN2LMNAMAPT | |
| SCHEMBL9373738 | 0.70 | NLRP3 (0.34) | NPSR1POLBSMN1; SMN2NPC1MAPT | |
| SCHEMBL14216927 | 0.70 | GAA (0.36) | TBK1 | |
| SCHEMBL9321113 | 0.69 | SMN1; SMN2 (0.38) | SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL9481342 | 0.69 | KDM4E (0.40) | POLBSMN1; SMN2MAPTALDH1A1HPGD | |
| SCHEMBL13168050 | 0.69 | GABRA1 (0.33) | HTTNPSR1SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL9318624 | 0.69 | MMP8 (0.42) | POLBSMN1; SMN2NPC1LMNAL3MBTL1 | |
| SCHEMBL9321131 | 0.68 | CA12 (0.40) | SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338860-A | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-08-16 | — | — | US | disclosed |